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Table 3 DGS 2018 treatment guidelines. Adapted from [40]

From: Five regions, five retinopathy screening programmes: a systematic review of how Portugal addresses the challenge

Diabetic retinopathy stage

Procedure and treatment

No disease visible or Mild NPDR

DR screening

NPDR moderate or severe

DR ophthalmologic consultation

Optical coherence tomography (OCT)

NPDR with DME focal or multifocal or PDR without DME

Fluorescein angiography (FA) and OCT

Laser therapy

PDR with MDE

Diffuse DME

FA + OCT

Combined DR therapy: Laser + Intravitreal injection of anti-vascular endothelial growth and/or long-acting corticosteroids

Advanced PDR with:

- Vitreous or sub hyaloid haemorrhage

- Retinal detachment

- Neovascular glaucoma

- Chronic DME with no response to treatment or refractory

DR chirurgic therapy: vitrectomy

Combined DR therapy: FA + OCT + Laser + Intravitreal injection of anti-vascular endothelial growth and/or long-acting corticosteroids

Corticosteroids extended-release injectable devices