Factors associated with response and remission from depression at 6-months of treatment in a retrospective cohort treated within an integrated care program

Table 5 Binary logistic regression models for ≥6 point reduction in PHQ-9 score in the first 6 months, controlling for baseline PHQ-8 score

Effect	PHQ-9 Outcome^a	OR	95% CI	p-value
Baseline Item 9 (Yes vs. No)	Δ PHQ-9 ≥ 6	0.86	(0.61, 1.22)	0.3964
Baseline PHQ-8 Score	Δ PHQ-9 ≥ 6	1.09	(1.05, 1.14)	< .0001
Baseline GAD-7 Score ≥ 10	Δ PHQ-9 ≥ 6	0.83	(0.56, 1.22)	0.3313
Baseline PHQ-8 Score	Δ PHQ-9 ≥ 6	1.09	(1.05, 1.14)	< .0001
Baseline PCL Score > 50	Δ PHQ-9 ≥ 6	0.80	(0.54, 1.20)	0.2800
Baseline PHQ-8 Score	Δ PHQ-9 ≥ 6	1.10	(1.05, 1.14)	< .0001
CO-ADJUSTED MODEL^b
Baseline PHQ-8 Score	Δ PHQ-9 ≥ 6	1.10	(1.05, 1.16)	< .0001
Baseline Item 9 (Yes vs. No)	Δ PHQ-9 ≥ 6	0.89	(0.63, 1.26)	0.5041
Baseline GAD-7 Score ≥ 10	Δ PHQ-9 ≥ 6	0.87	(0.59, 1.30)	0.4940
Baseline PCL Score > 50	Δ PHQ-9 ≥ 6	0.85	(0.56, 1.28)	0.4229
FULLY ADJUSTED MODEL^c
Baseline PHQ-8 Score	Δ PHQ-9 ≥ 6	1.10	(1.05, 1.15)	< .0001
Baseline Item 9 (Yes vs. No)	Δ PHQ-9 ≥ 6	0.89	(0.62, 1.26)	0.5017
Baseline GAD-7 Score ≥ 10	Δ PHQ-9 ≥ 6	0.88	(0.59, 1.31)	0.5382
Baseline PCL Score > 50	Δ PHQ-9 ≥ 6	0.83	(0.55, 1.26)	0.3837

^a Δ PHQ-9 ≥ 6 indicates a reduction of 6 or greater on the PHQ-9 relative to baseline
^bAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score
^cAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score, Majority Physician Visits, and Total Visit Count

ISSN: 1472-6963