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Table 5 Binary logistic regression models for ≥6 point reduction in PHQ-9 score in the first 6 months, controlling for baseline PHQ-8 score

From: Factors associated with response and remission from depression at 6-months of treatment in a retrospective cohort treated within an integrated care program

Effect PHQ-9 Outcomea OR 95% CI p-value
 Baseline Item 9 (Yes vs. No) Δ PHQ-9 ≥ 6 0.86 (0.61, 1.22) 0.3964
 Baseline PHQ-8 Score Δ PHQ-9 ≥ 6 1.09 (1.05, 1.14) < .0001
 Baseline GAD-7 Score ≥ 10 Δ PHQ-9 ≥ 6 0.83 (0.56, 1.22) 0.3313
 Baseline PHQ-8 Score Δ PHQ-9 ≥ 6 1.09 (1.05, 1.14) < .0001
 Baseline PCL Score > 50 Δ PHQ-9 ≥ 6 0.80 (0.54, 1.20) 0.2800
 Baseline PHQ-8 Score Δ PHQ-9 ≥ 6 1.10 (1.05, 1.14) < .0001
CO-ADJUSTED MODELb
 Baseline PHQ-8 Score Δ PHQ-9 ≥ 6 1.10 (1.05, 1.16) < .0001
 Baseline Item 9 (Yes vs. No) Δ PHQ-9 ≥ 6 0.89 (0.63, 1.26) 0.5041
 Baseline GAD-7 Score ≥ 10 Δ PHQ-9 ≥ 6 0.87 (0.59, 1.30) 0.4940
 Baseline PCL Score > 50 Δ PHQ-9 ≥ 6 0.85 (0.56, 1.28) 0.4229
FULLY ADJUSTED MODELc
 Baseline PHQ-8 Score Δ PHQ-9 ≥ 6 1.10 (1.05, 1.15) < .0001
 Baseline Item 9 (Yes vs. No) Δ PHQ-9 ≥ 6 0.89 (0.62, 1.26) 0.5017
 Baseline GAD-7 Score ≥ 10 Δ PHQ-9 ≥ 6 0.88 (0.59, 1.31) 0.5382
 Baseline PCL Score > 50 Δ PHQ-9 ≥ 6 0.83 (0.55, 1.26) 0.3837
  1. a Δ PHQ-9 ≥ 6 indicates a reduction of 6 or greater on the PHQ-9 relative to baseline
  2. bAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score
  3. cAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score, Majority Physician Visits, and Total Visit Count