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Table 4 Multinomial logistic regression models for continued elevated (PHQ-9 ≥ 10), response (5 ≤ PHQ-9 ≤ 9) and remission (PHQ-9 < 5) in the first 6 months, controlling for baseline PHQ-8 score

From: Factors associated with response and remission from depression at 6-months of treatment in a retrospective cohort treated within an integrated care program

Effect

PHQ-9 Outcomea

OR

95% CI

p-value

 Baseline Item 9 (Yes vs. No)

PHQ-9 < 5

0.49

(0.29, 0.82)

0.0070

5 ≤ PHQ-9 < 10

0.75

(0.51, 1.10)

0.1406

 Baseline PHQ-8 Score

PHQ-9 < 5

0.86

(0.80, 0.91)

< 0.0001

5 ≤ PHQ-9 < 10

0.89

(0.84, 0.93)

< 0.0001

 Baseline GAD-7 Score ≥ 10

PHQ-9 < 5

0.72

(0.43, 1.22)

0.2215

5 ≤ PHQ-9 < 10

0.72

(0.47, 1.10)

0.1300

 Baseline PHQ-8 Score

PHQ-9 < 5

0.85

(0.80, 0.91)

< 0.0001

5 ≤ PHQ-9 < 10

0.89

(0.85, 0.94)

< 0.0001

 Baseline PCL Score > 50

PHQ-9 < 5

0.45

(0.23, 0.88)

0.0202

5 ≤ PHQ-9 < 10

0.94

(0.60, 1.47)

0.7738

 Baseline PHQ-8 Score

PHQ-9 < 5

0.87

(0.81, 0.93)

< 0.0001

5 ≤ PHQ-9 < 10

0.88

(0.84, 0.93)

< 0.0001

CO-ADJUSTED MODELb

 Baseline PHQ-8 Score

PHQ-9 < 5

0.88

(0.82, 0.95)

0.0004

5 ≤ PHQ-9 < 10

0.90

(0.85, 0.95)

< 0.0001

 Baseline Item 9 (Yes vs. No)

PHQ-9 < 5

0.53

(0.31, 0.89)

0.0172

5 ≤ PHQ-9 < 10

0.76

(0.51, 1.13)

0.1730

 Baseline GAD-7 Score ≥ 10

PHQ-9 < 5

0.85

(0.50, 1.45)

0.5561

5 ≤ PHQ-9 < 10

0.72

(0.46, 1.13)

0.1495

 Baseline PCL Score > 50

PHQ-9 < 5

0.52

(0.26, 1.03)

0.0594

5 ≤ PHQ-9 < 10

1.06

(0.66, 1.69)

0.8178

FULLY ADJUSTED MODELc

 Baseline PHQ-8 Score

PHQ-9 < 5

0.88

(0.82, 0.94)

0.0003

5 ≤ PHQ-9 < 10

0.89

(0.85, 0.94)

< 0.0001

 Baseline Item 9 (Yes vs. No)

PHQ-9 < 5

0.53

(0.31, 0.89)

0.0169

5 ≤ PHQ-9 < 10

0.76

(0.51, 1.13)

0.1740

 Baseline GAD-7 Score ≥ 10

PHQ-9 < 5

0.87

(0.51, 1.48)

0.6038

5 ≤ PHQ-9 < 10

0.72

(0.46, 1.12)

0.1485

 Baseline PCL Score > 50

PHQ-9 < 5

0.51

(0.26, 1.01)

0.0529

5 ≤ PHQ-9 < 10

1.05

(0.66, 1.67)

0.8482

  1. aRelative to PHQ-9 ≥ 10
  2. bAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score
  3. cAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score, Majority Physician Visits, and Total Visit Count