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Table 4 Multinomial logistic regression models for continued elevated (PHQ-9 ≥ 10), response (5 ≤ PHQ-9 ≤ 9) and remission (PHQ-9 < 5) in the first 6 months, controlling for baseline PHQ-8 score

From: Factors associated with response and remission from depression at 6-months of treatment in a retrospective cohort treated within an integrated care program

Effect PHQ-9 Outcomea OR 95% CI p-value
 Baseline Item 9 (Yes vs. No) PHQ-9 < 5 0.49 (0.29, 0.82) 0.0070
5 ≤ PHQ-9 < 10 0.75 (0.51, 1.10) 0.1406
 Baseline PHQ-8 Score PHQ-9 < 5 0.86 (0.80, 0.91) < 0.0001
5 ≤ PHQ-9 < 10 0.89 (0.84, 0.93) < 0.0001
 Baseline GAD-7 Score ≥ 10 PHQ-9 < 5 0.72 (0.43, 1.22) 0.2215
5 ≤ PHQ-9 < 10 0.72 (0.47, 1.10) 0.1300
 Baseline PHQ-8 Score PHQ-9 < 5 0.85 (0.80, 0.91) < 0.0001
5 ≤ PHQ-9 < 10 0.89 (0.85, 0.94) < 0.0001
 Baseline PCL Score > 50 PHQ-9 < 5 0.45 (0.23, 0.88) 0.0202
5 ≤ PHQ-9 < 10 0.94 (0.60, 1.47) 0.7738
 Baseline PHQ-8 Score PHQ-9 < 5 0.87 (0.81, 0.93) < 0.0001
5 ≤ PHQ-9 < 10 0.88 (0.84, 0.93) < 0.0001
CO-ADJUSTED MODELb
 Baseline PHQ-8 Score PHQ-9 < 5 0.88 (0.82, 0.95) 0.0004
5 ≤ PHQ-9 < 10 0.90 (0.85, 0.95) < 0.0001
 Baseline Item 9 (Yes vs. No) PHQ-9 < 5 0.53 (0.31, 0.89) 0.0172
5 ≤ PHQ-9 < 10 0.76 (0.51, 1.13) 0.1730
 Baseline GAD-7 Score ≥ 10 PHQ-9 < 5 0.85 (0.50, 1.45) 0.5561
5 ≤ PHQ-9 < 10 0.72 (0.46, 1.13) 0.1495
 Baseline PCL Score > 50 PHQ-9 < 5 0.52 (0.26, 1.03) 0.0594
5 ≤ PHQ-9 < 10 1.06 (0.66, 1.69) 0.8178
FULLY ADJUSTED MODELc
 Baseline PHQ-8 Score PHQ-9 < 5 0.88 (0.82, 0.94) 0.0003
5 ≤ PHQ-9 < 10 0.89 (0.85, 0.94) < 0.0001
 Baseline Item 9 (Yes vs. No) PHQ-9 < 5 0.53 (0.31, 0.89) 0.0169
5 ≤ PHQ-9 < 10 0.76 (0.51, 1.13) 0.1740
 Baseline GAD-7 Score ≥ 10 PHQ-9 < 5 0.87 (0.51, 1.48) 0.6038
5 ≤ PHQ-9 < 10 0.72 (0.46, 1.12) 0.1485
 Baseline PCL Score > 50 PHQ-9 < 5 0.51 (0.26, 1.01) 0.0529
5 ≤ PHQ-9 < 10 1.05 (0.66, 1.67) 0.8482
  1. aRelative to PHQ-9 ≥ 10
  2. bAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score
  3. cAdjusted for Baseline PHQ-8 Score, Item 9, GAD-7 Score, and PCL Score, Majority Physician Visits, and Total Visit Count