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Table 2 Bioterrorism knowledge-based multiple-choice questions

From: Knowledge and preparedness of healthcare providers towards bioterrorism

Questions

n (%)

Q1. The deadliest form of anthrax is:

 ▪ Inhalation

783 (76.8)

 ▪ Cutaneous

111 (10.9)

 ▪ Gastrointestinal

72 (7.1)

 ▪ Bubonic (swollen lymph nodes)

53 (5.2)

Q2. What is a critical measure in preventing contact transmission of vaccinia virus (the agent used in the currently licensed smallpox vaccine)?

 ▪ Thorough hand washing after contact with the vaccination site

534 (53.3)

 ▪ Isolation of the vaccinated person

200 (20.0)

 ▪ Use of a porous bandage to cover the vaccination site

99 (9.9)

 ▪ Application of the vaccine at an anatomic site normally covered by clothing

94 (9.4)

 ▪ Antibacterial ointment applied to the vaccination site

74 (7.4)

Q3. “Which of the following diseases has the potential for the person-to-person spread?”

 ▪ Smallpox and plague

526 (51.5)

 ▪ Anthrax and plague

414 (40.5)

 ▪ Plague and botulism

41 (4.0)

 ▪ Botulism and brucellosis

41 (4.0)

Q4. Which of the following features help to distinguish the rash of smallpox from that of chickenpox?

 ▪ The smallpox rash is centrifugal (the majority of lesions are on the face and extremities), while the rash in chickenpox is central (the majority of lesions lie on the trunk).

471 (47.2)

 ▪ The initial smallpox lesions coincide with the onset of fever, while the fever in chickenpox precedes the rash by 2–3 days

260 (26.1)

 ▪ Various stages of lesion progression can be found at any one single location on a smallpox patient, while the lesions of chickenpox tend to all occur at the same stage of development.

191 (19.1)

 ▪ Lesions rarely occur on the palms and soles in smallpox, while lesions commonly occur on the palms and soles in chickenpox.

76 (7.6)

Q5. The most common early presenting syndrome associated with the majority of high-risk (“Category A”) bioterrorism-associated diseases (i.e., anthrax, botulism, plague, smallpox, tularaemia, and viral haemorrhagic fevers) is:

 ▪ Influenza-like illness

415 (40.8)

 ▪ Fever and rash

380 (37.4)

 ▪ Acute bloody diarrhoea

179 (17.6)

 ▪ Acute hepatitis

42 (4.1)

Q6. A pathognomonic chest X-ray finding of advanced inhalation anthrax is:

 ▪ Widened mediastinum

429 (42.6)

 ▪ Cavitation

293 (29.1)

 ▪ Normal chest X-ray despite dyspnoea and tachypnea

286 (28.4)

Q7. Epidemiologic features of a plague outbreak that may indicate an intentional release of the plague organism include:

 ▪ Location of infections outside of areas of known enzootic infection

391 (39.5)

 ▪ Occurrence in persons with known health risks such as chronic pulmonary disease

336 (33.9)

 ▪ Occurrence in areas with prior reported rodent deaths

263 (26.6)

Q8. Which of the following are high biological terrorism threats because of substantial morbidity and mortality, ease of production, efficient dissemination, stability in aerosol, or high infectivity?

 ▪ Anthrax, smallpox, botulism, and plague

331 (32.6)

 ▪ Anthrax, chickenpox, botulism, and plague

291 (28.6)

 ▪ Anthrax, smallpox, chickenpox, and plague

250 (24.6)

 ▪ Anthrax, smallpox, mumps, and plague

144 (14.2)

Q9. Smallpox has all of the following clinical features EXCEPT:

 ▪ The virus can only be spread through direct or indirect contact with open lesions (e.g., by touching an infected lesion or by contact with infected clothing or bedding).

307 (30.5)

 ▪ During the incubation period, the infected person looks and feels healthy and cannot infect others

279 (27.7)

 ▪ Infectivity is highest after the fever has begun and during the first 7–10 days following the appearance of the rash.

287 (28.5)

 ▪ The incubation period ranges from 7 to 17 days.

135 (13.4)

Q10. Which of the following symptoms is/are not commonly found in inhalation anthrax, and if present, could help to differentiate an upper respiratory tract infection from anthrax?

 ▪ Rhinorrhoea and sore throat

293 (28.7)

 ▪ Meningeal signs

389 (38.1)

 ▪ Dyspnoea

191 (18.7)

 ▪ Vomiting

140 (14.5)

Q11. According to KFMC policies, a physician who sees a patient he or she suspects of having anthrax or smallpox must notify the Ministry of Health:

 ▪ By phone as soon as the provisional diagnosis is established

265 (26.2)

 ▪ By phone as soon as the suspected diagnosis has been laboratory confirmed

390 (38.5)

 ▪ By mail, phone, or fax within 72 h

184 (18.2)

 ▪ Immediately after receiving written permission from the patient (or his/her legal guardian)

174 (17.2)

Q12. According to KFMC policies, a physician who sees a patient he or she suspects of having anthrax or smallpox must notify the Ministry of Health:

 ▪ By phone as soon as the provisional diagnosis is established

265 (26.2)

 ▪ By phone as soon as the suspected diagnosis has been laboratory confirmed

390 (38.5)

 ▪ By mail, phone, or fax within 72 h

184 (18.2)

 ▪ Immediately after receiving written permission from the patient (or his/her legal guardian)

174 (17.2)

  1. Because of missing data in responses, items have various denominators
  2. The questions have been ordered from the most to the least correct answers