Table 3 Accuracy of Electronic Prescribing Data and Diagnostic Codes in Administrative Health Data in Detecting Adverse Drug Events, Overall and by Medication Class
From: Detection of adverse drug events in e-prescribing and administrative health data: a validation study
| Data Source |
Sensitivity (95% CI) |
Specificity (95% CI) |
PPV (95% CI) |
NPV (95% CI) |
|---|---|---|---|---|
| All Patients | ||||
| Electronic Prescribing Data | 9.7% (4.9–16.6%) | 95.0% (92.8–96.6%) | 27.5% (14.6–43.9%) | 84.1% (81.1–86.8%) |
| Adminsitrative Health Dataa | 7.0% (3.1–13.4%) | 90.6% (87.9–92.9%) | 12.9% (5.7–23.9%) | 83.1% (79.9–85.9%) |
| Electronic Prescribing & Administrative Health Dataa | 14.0% (8.2–21.8%) | 86.1% (83.0–88.8%) | 16.7% (9.8–25.7%) | 83.5% (80.2–86.4%) |
| Patients Prescribed an Antidepressant | ||||
| Electronic Prescribing Data | 13.5% (6.7–23.5%) | 95.6% (92.1–97.9%) | 50.0% (27.2–72.8%) | 77.3% (72.0–82.1%) |
| Adminsitrative Health Dataa | 5.4% (1.5–13.3%) | 94.7% (93.8–98.8%) | 36.4% (10.9–69.2%) | 76.0% (71.0–80.9%) |
| Electronic Prescribing & Administrative Health Dataa | 16.2% (8.7–26.6%) | 92.5% (88.3–95.6%) | 41.4% (23.5–61.1%) | 77.3% (71.9–82.1%) |
| Patients Prescribed an Antihypertensive | ||||
| Electronic Prescribing Data | 2.5% (0.0–13.2%) | 94.5% (91.6–96.7%) | 5.0% (0.1–24.9%) | 89.3% (85.7–92.3%) |
| Adminsitrative Health Dataa | 10.0% (2.8–23.7%) | 86.4% (82.3–89.9%) | 7.8% (2.2–18.9%) | 89.3% (85.4–92.4%) |
| Electronic Prescribing & Administrative Health Dataa | 10.0% (2.8–23.7%) | 81.8% (77.3–85.7%) | 6.0% (1.7–14.6%) | 88.7% (84.7–92.0%) |