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Table 5 Comparison of biological parameters for sickle cell patients before and after the Implementation of Standardized and Regular Follow-Ups

From: Improvement of SCD morbimortality in children: experience in a remote area of an African country

 

Year 1

Year 2

p-value

Biological Parameters

Follow-up without any intervention

Median (+/− SD)

Standardized and regular follow-up

Median (+/− SD)

HB (g/L)

50 (54 ± 20)

76 (76 ± 14)

< 0.001

RBC (×  106/mm3)

2.0 (64 ± 25)

2.9 (86 ± 19)

< 0.001

HCT (%)

15 (61 ± 21)

23 (84 ± 15)

< 0.00

MCV (fL)

81 (129 ± 20)

82 (125 ± 13)

0.176

MCH (pg)

25 (20 ± 38)

25 (16 ± 35)

0.19

WBC (×  103/mm3)

9.6 (374 ± 201)

8.4 (270 ± 109)

< 0.001

Lymphocytes (× 103/mm3)

4.1 (364 ± 293)

3.2 (239 ± 145)

< 0.001

Neutrophils (× 103/mm3)

4.7 (375 ± 205)

4.4 (369 ± 137)

0.554

Platelets (× 103/mm3)

260 (248 ± 131)

328 (317 ± 108)

< 0.001

  1. The averages of biological parameters represent the percentage of the normal lower limit of the reference range (% LLN) ± SD of the evolution of each patient in relation to themself
  2. HB hemoglobin, RBC red blood cells, HCT hematocrit, MCV mean corpuscular volume, WBC white blood cells, MCH mean corpuscular hemoglobin