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Table 1 Input parameters for market dynamics after patent expiration

From: Use of budget savings from patent expiration of cancer drugs to improve affordability and accessibility

Variables Years after patent expiration
1st year 2nd year 3rd year 4th year 5th year
Market share of generics/biosimilar
 Chemical generics 5.0% 7.1% 9.2% 11.3% 13.4%
 Biosimilars 3.1% 12.5% 12.5% 12.5% 12.5%
Market growth      
 Chemical drugs 1.3% 1.4% 1.4% 1.4% 1.4%
 Biologics 4.0% 0.0% 0.0% 0.0% 0.0%
Price level of originatorsa
 Chemical drugs 75% 60% 60% 53% 53%
 Biologics 80% 80% 80% 80% 80%
Price level of generics/biosimilarsa
 Chemical generics 58% 57% 55% 51% 51%
 Biosimilars 72% 57% 57% 57% 57%
  1. a For the price level, the percentages at each year after patent expiration are the relative ratio compared with the price (=100%) at the time of patent expiration
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