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Table 4 Mean annual treatment cost of each epilepsy patient with respect to top five prescribing anti-epileptic drugs as monotherapy

From: Analysis of treatment adherence and cost among patients with epilepsy: a four‐year retrospective cohort study in Pakistan

  Mean cost for Continuers Mean cost for Switchers Mean cost for Discontinuers Mean cost for study cohort
  PKRa± SDb USDc± SD PKR ± SD USD ± SD PKR ± SD USD ± SD PKR ± SD USD ± SD
Levetiracetam 14709.5 ± 3297.2 90.4 ± 20.2 6058.7 ± 1435.3 37.2 ± 8.8 6246.5 ± 1278.2 38.3 ± 7.8 9004.9 ± 2003.5 55.3 ± 12.3
Valproic acid 3723.1 ± 912.2 22.8 ± 5.6 8425.3 ± 2038.4 51.7 ± 12.5 1487.6 ± 437.6 9.14 ± 2.6 4545.5 ± 1129.4 27.9 ± 6.9
Carbamazepine 1350.5 ± 405.7 8.3 ± 2.4 7468.6 ± 1974.2 45.9 ± 12.1 853.7 ± 237.9 5.2 ± 1.4 3224.2 ± 872.6 19.8 ± 5.3
Lamotrigine 22995.2 ± 4397.3 141.3 ± 27.0 9574.5 ± 2044.9 58.8 ± 12.5 9657.2 ± 1949.2 59.3 ± 11.9 14075.5 ± 2797.1 86.5 ± 17.1
Lacosamide 18980.1 ± 3743.6 116.6 ± 23.0 11478.0 ± 2187.3 70.5 ± 13.4 8574.1 ± 1887.3 52.6 ± 11.5 13010.6 ± 2606.0 79.9 ± 16.0
Others 7665.0 ± 1825.5 47.1 ± 11.2 11485.8 ± 2295.6 70.6 ± 14.1 2547.6 ± 578.7 15.6 ± 3.5 7232.8 ± 1566.6 44.4 ± 9.6
Total Mean Cost 11570.5 ± 2430.2 71.1 ± 14.9 9081.8 ± 1995.9 55.8 ± 12.2 4894.4 ± 1061.4 30.0 ± 6.5 8515.5 ± 1829.2 52.3 ± 11.2
Total annual cost 69423.0 ± 14581.5 426.6 ± 89.6 54490.9 ± 11975.7 334.9 ± 73.6 29366.6 ± 6368.9 180.4 ± 39.1 51093.5 ± 10975.3 314.0 ± 67.4
  1. Phenobarbital, phenytoin, gabapentin, pregabalin and oxcarbazepine were categorized as others AEDs
  2. aPakistani rupees
  3. bStandard deviation
  4. cUnited States Dollar
  5. *1 USD = 154.38 PKR (At: 27-Jan-2020)