Table 5 Estimated additional costs of broad-spectrum antibiotic prescription in ambulatory care (unit = million USD)a
From: Cost of inappropriate antimicrobial use for upper respiratory infection in Japan
Class | 2013 | 2014 | 2015 | 2016 |
|---|---|---|---|---|
Third-generation cephalosporins | 134·7 (132·0–137·5) | 114·1 (111·9–116·3) | 113·8 (111·5–116·1) | 93·7 (91·7–95·7) |
Macrolides | 133·8 (130·6–137·1) | 101·7 (99·3–104·1) | 108·1 (105·6–110·5) | 93·4 (91·2–95·6) |
Fluoroquinolones | 135·4 (131·2–139·7) | 108·1 (104·9–111·4) | 111·2 (107·9–114·6) | 93·5 (90·6–96·5) |
Total | 403·9 (394·8–414·3) | 323·9 (316·1–331·8) | 333·1 (325·0–341·2) | 280·0 (273·5–287·8) |