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Table 2 Conventional Testing Regime: Public Sexual Health Clinic Setting (Funded by State Government)

From: Economic evaluation of alternative testing regimes and settings to detect undiagnosed HIV in Australia

 

True HIV Positive (PHIV )

True HIV Negative (1 − PHIV)

Outcomes

HIV Positive

(EIA+ & WB+)

False HIV Negative

(EIA-)

False HIV Positive

(EIA+ & WB-)

True HIV Negative

(EIA-)

Probability of result

(PHIVSenEIASenWB )

(PHIV (1 − SenEIA))

((1 − PHIV)  (1 − SpecEIA) SpecWB)

(1 − PHIV) SpecEIA

Inputs

Visit 1: Initial Screening

  Consult time

30 Min

30 Min

30 Min

30 Min

  Staff Wage (Rate/Hour):

$45.12

$45.12

$45.12

$45.12

  Staffing

Clinical Nurse

Clinical Nurse

Clinical Nurse

Clinical Nurse

Pathology costs

  EIA

$18.54

$18.54

$18.54

$18.54

  WB confirmatory

$84.54

 

$84.54

 

Visit 2: Test Results

  Consult time

60 Min

30 Min

30 Min

30 Min

  Staff Wage (Rate/Hour):

$78.00

$45.12

$45.12

$45.12

  Staffing

Staff specialist

(Level 18)

Clinical Nurse

Clinical Nurse

Clinical Nurse

Total Cost of Each Outcome

$203.64

$63.67

$148.21

$63.67

Average cost per person tested

=(PHIVSenEIASenWB) AC per True HIV PositiveEIA + , WB+ + (PHIV (1 − SenEIA)) AC per False HIV NegativeEIA + ((1 − PHIV) SpecEIA) AC per True HIV NegativeEIA + ((1 − PHIV)  (1 − SpecEIA) SpecWB)) AC per False HIV PositiveEIA + , WB

Average number of tests for a positive diagnosis

\( =\frac{1}{P_{HIV}\ast Se{n}_{EIA}\ast Se{n}_{WB}} \)

  1. Note: AC Average Cost, EIA fourth generation enzyme immunoassay test, P Probability, Sen Sensitivity, Spec Specificity, WB Western Blot Test, + reactive test result, − nonreactive test result