Elixhauser comorbidities | Alive cohort (%) | Mortality cohort (%) | SMD | Adjusted odds ratio (95% CI) | Weights | ||
---|---|---|---|---|---|---|---|
 | Swiss derivation sample | VWa | Swiss | VWa | Swiss | ||
bDerivation group | 2,975,887 (97.7) | 71,449 (2.3) | Â | Â | Â | Â | Â |
Congestive heart failure | 163,685 (5.5) | 16,333 (22.9) | 0.514 | 1.96 (1.85–2.07) | 3.07 (3.00–3.14) | 7 | 13 |
Cardiac arrhythmias | 341,280 (11.5) | 20,754 (29.0) | 0.448 | 1.71 (1.62–1.80) | 1.69 (1.66–1.73) | 5 | 6 |
Valvular disease | 117,450 (3.9) | 6568 (9.2) | 0.213 | 0.91 (0.82–0.99) | 0.92 (0.89–0.95) | -1 | -1 |
Pulmonary circulation disorders | 53,292 (1.8) | 4813 (6.7) | 0.247 | 1.48 (1.34–1.62) | 1.62 (1.57–1.68) | 4 | 6 |
Peripheral vascular disorders | 141,051 (4.7) | 6912 (9.7) | 0.192 | 1.26 (1.17–1.36) | 1.27 (1.24–1.31) | 2 | 3 |
Hypertension (uncomplicated) | 676,609 (22.7) | 15,692 (22.0) | 0.019 | – | 0.69 (0.68–0.70) | 0 | −4 |
Hypertension (complicated) | 218,656 (7.3) | 11,003 (15.4) | 0.256 | – | 0.79 (0.77–0.81) | 0 | −3 |
Paralysis | 61,546 (2.1) | 5153 (7.2) | 0.246 | 1.93 (1.75–2.12) | 2.60 (2.52–2.69) | 7 | 11 |
Other neurological disorders | 120,045 (4.0) | 8011 (11.2) | 0.273 | 1.83 (1.70–1.96) | 2.45 (2.39–2.52) | 6 | 10 |
Chronic pulmonary disease | 170,770 (5.7) | 8269 (11.6) | 0.209 | 1.36 (1.29–1.44) | 1.31 (1.27–1.34) | 3 | 3 |
Diabetes, uncomplicated | 245,817 (8.3) | 9059 (12.7) | 0.145 | – | 1.09 (1.06–1.11) | 0 | 1 |
Diabetes, complicated | 66,161 (2.2) | 2763 (3.9) | 0.096 | – | 0.89 (0.86–0.93) | 0 | −1 |
Hypothyroidism | 126,062 (4.2) | 3454 (4.8) | 0.029 | – | 0.76 (0.74–0.79) | 0 | −3 |
Renal failure | 289,047 (9.7) | 20,526 (28.7) | 0.497 | 1.63 (1.54–1.73) | 2.06 (2.02–2.11) | 5 | 8 |
Liver disease | 49,916 (1.7) | 5822 (8.1) | 0.303 | 2.97 (2.73–3.22) | 3.83 (3.7–3.97) | 11 | 16 |
Peptic ulcer disease, excluding bleeding | 5808 (0.2) | 258 (0.4) | 0.032 | – | – | 0 | 0 |
AIDS/HIV | 2300 (0.1) | 85 (0.1) | 0.013 | – | – | 0 | 0 |
Lymphoma | 25,049 (0.8) | 1759 (2.5) | 0.127 | 2.55 (2.31–2.81) | 2.19 (2.07–2.31) | 9 | 9 |
Metastatic cancer | 119,667 (4.0) | 18,907 (26.5) | 0.657 | 3.30 (3.10–3.52) | 4.09 (3.98–4.21) | 12 | 17 |
Solid tumour without metastasis | 268,298 (9.0) | 24,046 (33.7) | 0.631 | 1.47 (1.39–1.56) | 2.36 (2.3–2.42) | 4 | 10 |
Rheumatoid arthritis/collagen vascular diseases | 47,305 (1.6) | 1254 (1.8) | 0.013 | – | 0.91 (0.86–0.97) | 0 | −1 |
Coagulopathy | 90,551 (3.0) | 9528 (13.3) | 0.382 | 1.30 (1.22–1.40) | 2.12 (2.07–2.18) | 3 | 9 |
Obesity | 68,155 (2.3) | 1011 (1.4) | 0.065 | 0.64 (0.53–0.77) | 0.59 (0.56–0.63) | −4 | −6 |
Weight loss | 98,545 (3.3) | 9527 (13.3) | 0.369 | 1.85 (1.67–2.04) | 1.67 (1.63–1.71) | 6 | 6 |
Fluid and electrolyte disorders | 257,618 (8.7) | 17,440 (24.4) | 0.434 | 1.61 (1.53–1.69) | 1.58 (1.55–1.61) | 5 | 5 |
Blood loss anaemia | 19,759 (0.7) | 685 (1.0) | 0.033 | 0.81 (0.70–0.93) | 0.66 (0.60–0.71) | −2 | −5 |
Deficiency anaemia | 72,290 (2.4) | 1886 (2.6) | 0.013 | 0.80 (0.71–0.90) | 0.54 (0.51–0.56) | −2 | −7 |
Alcohol abuse | 96,708 (3.2) | 3086 (4.3) | 0.056 | – | 0.75 (0.72–0.78) | 0 | −3 |
Drug abuse | 38,044 (1.3) | 583 (0.8) | 0.045 | 0.50 (0.42–0.60) | 0.67 (0.61–0.73) | −7 | −5 |
Psychoses | 29,598 (1.0) | 404 (0.6) | 0.049 | – | 0.72 (0.65–0.79) | 0 | −4 |
Depression | 173,898 (5.8) | 3715 (5.2) | 0.028 | 0.73 (0.67–0.80) | 0.73 (0.70–0.75) | −3 | −3 |