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Table 3 Outcomes – Unadjusted separate and adjusted multiple models

From: Community care coordination for stroke survivors: results of a complex intervention study

Utilization of outpatient specialist services: Mixed effects logistic regression (n = 361 individuals / 91 matched groups)

 

Unadjusted separate models

Adjusted multiple model

 

Odds ratio (95% CI)

p-value

Odds ratio (95% CI)

p-value

Intervention (ref.: controls)

4.02 (2.35–6.86)

< 0.001

4.75 (2.71–8.31)

< 0.001

Age (years)

0.97 (0.95–0.99)

0.004

0.97 (0.94–0.996)

0.020

Female Sex (ref.: males)

0.76 (0.50–1.15)

0.191

0.87 (0.54–1.39)

0.560

Pre-stroke Care Dependency

0.58 (0.36–0.94)

0.026

0.78 (0.39–1.37)

0.389

Stroke Type

 - Ischemia (Ref.)

1

 

1

 

 - Hemorrhage

1.32 (0.65–2.68)

0.446

1.33 (0.67–1.01)

0.464

 - TIA

0.79 (0.29–2.11)

0.638

0.67 (0.23–1.96)

0.469

 - non-specified

1.24 (0.39–4.00)

0.715

1.01 (0.29–3.60)

0.983

 Number of comorbidities

0.81 (0.71–0.92)

0.002

0.77 (0.66–0.90)

0.001

Recurrent strokes: Mixed effects Poisson regression (n = 361 individuals / 91 matched groups)

 

Unadjusted separate models

Adjusted multiple model

 
 

IRR (95% CI)

p-value

Odds ratio (95% CI)

p-value

 Intervention (ref.: controls)

0.78 (0.39–1.57)

0.491

0.76 (0.38–1.54)

0.451

 Age (years)

1.01 (0.97–1.04)

0.757

1.02 (0.98–1.05)

0.301

 Female Sex (ref.: males)

0.51 (0.27–0.94)

0.031

0.49 (0.26–0.93)

0.028

 Pre-stroke Care Dependency

0.70 (0.33–1.48)

0.349

0.67 (0.31–1.44)

0.309

Stroke Type

 - Ischemia (Ref.)

1

 

1

 

 - Hemorrhage

1.32 (0.54–3.20)

0.541

1.23 (0.52–2.90)

0.636

 - TIA

0.39 (0.05–2.92)

0.362

0.36 (0.05–2.6)

0.308

 - non-specified

1.82 (0.53–6.16)

0.339

1.31 (0.40–4.34)

0.664

Number of comorbidities

1.00 (0.84–1.19)

0.973

1.03 (0.86–1.23)

0.743

 Hospital readmissions: Mixed effects negative binomial regression (n = 361 individuals / 91 matched groups)

 

Unadjusted separate models

Adjusted multiple model

 
 

IRR (95% CI)

p-value

IRR (95% CI)

p-value

Intervention (ref.: controls)

0.45 (0.31–0.65)

< 0.001

0.42 (0.29–0.61)

< 0.001

Age (years)

1.01 (1.00–1.03)

0.109

 

0.181

Female Sex (ref.: males)

1.01 (0.75–1.36)

0.940

0.89 (0.66–1.20)

0.452

Pre-stroke Care Dependency

1.62 (1.17–2.25)

0.004

1.38 (0.98–1.94)

0.062

Stroke Type

 - Ischemia (Ref.)

1

 

1

 

 - Hemorrhage

1.03 (0.62–1.69)

0.916

1.10 (0.68–1.79)

0.703

 - TIA

0.96 (0.49–1.85)

0.899

1.00 (0.53–1.89)

1.000

 - non-specified

0.67 (0.28–1.64)

0.382

0.69 (0.29–1.66)

0.407

 Number of comorbidities

1.12 (1.03–1.23)

0.010

1.12 (1.03–1.22)

0.012

Mortality: Frailty survival model (n = 361 individuals / 91 matched groups, 38 events)

 

Unadjusted separate models

Adjusted multiple model

 
 

Hazard ratio (95% CI)

p-value

Hazard ratio (95% CI)

p-value

Intervention (ref.: controls)

0.74 (0.32–1.68)

0.57

0.65 (0.28–1.49

0.386

Age (years)

1.11 (1.06–1.16)

< 0.001

1.11 (1.05–1.16)

< 0.001

Female Sex (ref.: males)

0.99 (0.46–2.10)

0.970

0.56 (0.26–1.23)

0.150

Pre-stroke Care Dependency

2.93 (1.38–6.24)

0.005

1.54 (0.68–3.506)

0.300

Stroke Type

 - Ischemia (Ref.)

1

 

1

 

 - Hemorrhage

1.32 (0.42–4.13)

0.630

1.37 (0.46–4.11)

0.570

 - TIA

/

/

/

/

 - non-specified

0.76 (0.08–7.39)

0.810

1.23 (0.97–11.60)

0.860

Number of comorbidities

1.25 (1.02–1.52)

0.028

1.19 (0.97–1.46)

0.093

Hospital readmission costs: Linear mixed model (n = 361 individuals / 91 matched groups)

 

Unadjusted separate models

Adjusted multiple model

 
 

β (95 % CI)

p-value

β (95 % CI)

p-value

constant

 

5.50 (4.66–6.34)

< 0.001

Intervention (ref.: controls)

−0.34 (−0.54 - -0.14)

0.001

−0.37 (−0.57 - -0.18)

< 0.001

Age (years)

0.01 (0.001–0.02)

0.024

0.01 (− 0.002–0.02)

0.131

Female Sex (ref.: males)

−0.06 (− 0.24–0.11)

0.480

−0.12 (− 0.30–0.05)

0.158

Pre-stroke Care Dependency

 

0.28 (0.07–0.49)

0.009

Stroke Type

 - Ischemia (Ref.)

    

 - Hemorrhage

0.20 (−0.10–0.51)

0.185

0.24 (− 0.06–0.53)

0.115

 - TIA

− 0.05 (− 0.46–0.36)

0.802

0.03 (− 0.37–0.43)

0.885

 - non-specified

−0.01 (− 0.50–0.50)

0.980

0.04 (− 0.45–0.53)

0.874

 Number of comorbidities

0.07 (0.02–0.12)

0.012

0.06 (0.01–0.12)

0.005

Models with log-transformed costs as dependent variable