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Table 2 Parameter estimates (95% confidence intervals) for average HbA1c (mmol/mol) levels over the follow-up

From: Impact of co-payment level increase of antidiabetic medications on glycaemic control: an interrupted time-series study among Finnish patients with type 2 diabetes

 

Baseline level at 01/2014

Pre-policy change trend in 01/2014–12/2016

Change in level at the time of the policy change in 01/2017

Post-policy change trend in 02/2017–9/2019

All patients (n = 8143)

52.40 (51.88 to 52.91)

0.07 (0.04 to 0.09)

0.81 (0.04 to 1.58)

0.03 (− 0.03 to 0.08)

Subgroup analyses:

 Patients aged < 75 years (n = 5203)

52.05 (51.50 to 52.60)

0.06 (0.04 to 0.09)

0.79 (− 0.04 to 1.62)

0.04 (− 0.02 to 0.10)

 Patients aged ≥75 years (n = 2940)

53.39 (52.59 to 54.19)

0.06 (0.02 to 0.10)

1.53 (0.40 to 2.66)

0.00 (−0.08 to 0.09)

  ≤ 10 years duration of T2D (n = 4243)

47.35 (46.80 to 47.90)

0.06 (0.04 to 0.09)

0.68 (−0.03 to 1.39)

0.05 (− 0.01 to 0.11)

  > 10–15 years duration of T2D (n = 1976)

53.15 (52.41 to 53.89)

0.09 (0.06 to 0.13)

0.85 (−0.29 to 1.99)

0.02 (− 0.06 to 0.09)

  > 15 years duration of T2D (n = 1924)

59.76 (58.57 to 60.95)

0.03 (−0.02 to 0.09)

1.49 (− 0.11 to 3.09)

0.02 (− 0.11 to 0.15)

Used only metformin in 2016 (n = 2271)

42.79 (42.44 to 43.14)

0.06 (0.04 to 0.07)

1.28 (0.83 to 1.73)

0.05 (0.02 to 0.09)

Used metformin and other OAD in 2016 (n = 1430)

49.85 (49.17 to 50.53)

0.09 (0.06 to 0.12)

0.92 (−0.10 to 1.94)

0.06 (−0.01 to 0.13)

Used only other diabetes medications than insulin or metformin in 2016 (n = 726)

46.71 (45.99 to 47.43)

0.04 (0.01 to 0.08)

3.56 (2.50 to 4.62)

0.02 (−0.06 to 0.10)

Used insulin and OAD (incl. metformin) in 2016 (n = 2112)

61.78 (60.88 to 62.68)

0.06 (0.02 to 0.10)

0.92 (−0.39 to 2.22)

−0.03 (− 0.12 to 0.07)

Used only insulin in 2016 (n = 577)

62.18 (60.98 to 63.38)

−0.00 (− 0.06 to 0.05)

0.42 (−1.28 to 2.12)

0.07 (− 0.06 to 0.20)

  1. Abbreviations: OAD oral antidiabetic drug;, T2D type 2 diabetes