N (%) / Median (IQR) in total population (missing excluded) | Center-level range (median or percentage) | Total number of patients | Missing N (%) | P-value* | |
---|---|---|---|---|---|
Age (years) | 72 (61–80) | 68–77 | 3279 | 0 | 0.001 |
Men | 1696 (52) | 39–55 | 3279 | 0 | 0.790 |
Medical History | |||||
Previous Stroke | 546 (17) | 0–26 | 3252 | 27 (0.8) | < 0.001 |
Atrial Fibrillation | 772 (24) | 13–37 | 3236 | 43 (1.3) | < 0.001 |
Myocardial Infarction | 453 (14) | 4–18 | 3212 | 67 (2.0) | 0.16 |
Peripheral Arterial Disease | 301 (9) | 4–22 | 3211 | 68 (2.1) | < 0.001 |
Hypertension | 1688 (53) | 41–67 | 3213 | 66 (2.0) | < 0.001 |
Diabetes | 532 (16) | 12–25 | 3255 | 24 (0.7) | 0.09 |
Hypercholesterolemia | 967 (31) | 15–50 | 3136 | 143 (4.4) | < 0.001 |
Pre-stroke modified Rankin Scale score | 3207 | 72 (2.2) | < 0.001 | ||
0 | 2170 (68) | 45–87 | |||
1 | 424 (13) | 3–19 | |||
2 | 241 (8) | 0–16 | |||
≥ 3 | 372 (12) | 5–25 | |||
Location of occlusion | 3119 | 160 (4.99) | < 0.001 | ||
M1 | 1815 (58) | 45–70 | |||
M2 | 455 (15) | 4–31 | |||
Intracranial ICA | 161 (5) | 0–10 | |||
ICA-T | 663 (21) | 9–27 | |||
Other (M3/anterior) | 25 (1) | 0–4 | |||
Collateral grade | 3072 | 207 (6.3) | < 0.001 | ||
0 (Absent) | 187 (6) | 0–9 | |||
1 (< 50%) | 1100 (36) | 17–46 | |||
2 (> 50% but < 100%) | 1190 (39) | 33–61 | |||
3 (100%) | 595 (19) | 10–37 | |||
Baseline NIHSS score | 16 (11–20) | 13–17 | 3224 | 55 (1.7) | < 0.001 |
Transferred patients from other hospital | 1783 (54) | 0–77 | 3279 | 0 | < 0.001 |
Time from onset to arrival at the ED (min) | 135 (65–195) | 52–160 | 3155 | 124 (3.8) | < 0.001 |
Predicted probability of good functional outcomea | 41 (20–62) | 17–50 | 2550 | 729 (22.2) | 0.004 |