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Table 1 Case-mix characteristics of patients treated in intervention centers in MR CLEAN Registry

From: Improving quality of stroke care through benchmarking center performance: why focusing on outcomes is not enough

 

N (%) / Median (IQR) in total population (missing excluded)

Center-level range (median or percentage)

Total number of patients

Missing N (%)

P-value*

Age (years)

72 (61–80)

68–77

3279

0

0.001

Men

1696 (52)

39–55

3279

0

0.790

Medical History

 Previous Stroke

546 (17)

0–26

3252

27 (0.8)

< 0.001

 Atrial Fibrillation

772 (24)

13–37

3236

43 (1.3)

< 0.001

 Myocardial Infarction

453 (14)

4–18

3212

67 (2.0)

0.16

 Peripheral Arterial Disease

301 (9)

4–22

3211

68 (2.1)

< 0.001

 Hypertension

1688 (53)

41–67

3213

66 (2.0)

< 0.001

 Diabetes

532 (16)

12–25

3255

24 (0.7)

0.09

 Hypercholesterolemia

967 (31)

15–50

3136

143 (4.4)

< 0.001

Pre-stroke modified Rankin Scale score

  

3207

72 (2.2)

< 0.001

 0

2170 (68)

45–87

   

 1

424 (13)

3–19

   

 2

241 (8)

0–16

   

 ≥ 3

372 (12)

5–25

   

Location of occlusion

  

3119

160 (4.99)

< 0.001

 M1

1815 (58)

45–70

   

 M2

455 (15)

4–31

   

 Intracranial ICA

161 (5)

0–10

   

 ICA-T

663 (21)

9–27

   

 Other (M3/anterior)

25 (1)

0–4

   

Collateral grade

  

3072

207 (6.3)

< 0.001

 0 (Absent)

187 (6)

0–9

   

 1 (< 50%)

1100 (36)

17–46

   

 2 (> 50% but < 100%)

1190 (39)

33–61

   

 3 (100%)

595 (19)

10–37

   

Baseline NIHSS score

16 (11–20)

13–17

3224

55 (1.7)

< 0.001

Transferred patients from other hospital

1783 (54)

0–77

3279

0

< 0.001

Time from onset to arrival at the ED (min)

135 (65–195)

52–160

3155

124 (3.8)

< 0.001

Predicted probability of good functional outcomea

41 (20–62)

17–50

2550

729 (22.2)

0.004

  1. IQR Interquartile range, ICA-T internal carotid artery terminus, M1/M2 middle cerebral artery, NIHSS National Institutes of Health Stroke Scale, ED Emergency department
  2. aPredicted probability (%) of good functional outcome (modified Rankin Scale score 0–2 at 90 days) is based on an individual-level logistic regression model predicting good functional outcome from the case-mix variables included in this table. See Supplementary Table 1 for details of case-mix characteristics of patients treated in each intervention center
  3. *P-value is based on comparison between 17 centers using a non-parametric Kruskal Wallis test for continuous variables or Pearson’s chi-square statistic for categorical variables