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Table 1 Case-mix characteristics of patients treated in intervention centers in MR CLEAN Registry

From: Improving quality of stroke care through benchmarking center performance: why focusing on outcomes is not enough

  N (%) / Median (IQR) in total population (missing excluded) Center-level range (median or percentage) Total number of patients Missing N (%) P-value*
Age (years) 72 (61–80) 68–77 3279 0 0.001
Men 1696 (52) 39–55 3279 0 0.790
Medical History
 Previous Stroke 546 (17) 0–26 3252 27 (0.8) < 0.001
 Atrial Fibrillation 772 (24) 13–37 3236 43 (1.3) < 0.001
 Myocardial Infarction 453 (14) 4–18 3212 67 (2.0) 0.16
 Peripheral Arterial Disease 301 (9) 4–22 3211 68 (2.1) < 0.001
 Hypertension 1688 (53) 41–67 3213 66 (2.0) < 0.001
 Diabetes 532 (16) 12–25 3255 24 (0.7) 0.09
 Hypercholesterolemia 967 (31) 15–50 3136 143 (4.4) < 0.001
Pre-stroke modified Rankin Scale score    3207 72 (2.2) < 0.001
 0 2170 (68) 45–87    
 1 424 (13) 3–19    
 2 241 (8) 0–16    
 ≥ 3 372 (12) 5–25    
Location of occlusion    3119 160 (4.99) < 0.001
 M1 1815 (58) 45–70    
 M2 455 (15) 4–31    
 Intracranial ICA 161 (5) 0–10    
 ICA-T 663 (21) 9–27    
 Other (M3/anterior) 25 (1) 0–4    
Collateral grade    3072 207 (6.3) < 0.001
 0 (Absent) 187 (6) 0–9    
 1 (< 50%) 1100 (36) 17–46    
 2 (> 50% but < 100%) 1190 (39) 33–61    
 3 (100%) 595 (19) 10–37    
Baseline NIHSS score 16 (11–20) 13–17 3224 55 (1.7) < 0.001
Transferred patients from other hospital 1783 (54) 0–77 3279 0 < 0.001
Time from onset to arrival at the ED (min) 135 (65–195) 52–160 3155 124 (3.8) < 0.001
Predicted probability of good functional outcomea 41 (20–62) 17–50 2550 729 (22.2) 0.004
  1. IQR Interquartile range, ICA-T internal carotid artery terminus, M1/M2 middle cerebral artery, NIHSS National Institutes of Health Stroke Scale, ED Emergency department
  2. aPredicted probability (%) of good functional outcome (modified Rankin Scale score 0–2 at 90 days) is based on an individual-level logistic regression model predicting good functional outcome from the case-mix variables included in this table. See Supplementary Table 1 for details of case-mix characteristics of patients treated in each intervention center
  3. *P-value is based on comparison between 17 centers using a non-parametric Kruskal Wallis test for continuous variables or Pearson’s chi-square statistic for categorical variables