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Table 3 SAFER Conception total cost per couple (2017 $US)

From: Estimated costs for the delivery of safer conception strategies for HIV-discordant couples in Zimbabwe: a cost analysis

Individual strategiesa

ART-VL

PrEP

Semen-washing

AVI

 

 SAFER Study

$1615

$1229

$1190

$769

 

 High Intensity (Study-level) with Real-world Prices (Scenario 1)

$431

$403

$563

$185

 

 Target Intensity, Incremental Cost Added to CP (Scenario 2)

$302

$266

$360

$73

 

 Target Intensity, Incremental Cost Added to SOC (Scenario 3)

$132

$88

$356

$62

 

Strategy combinationsa

ART-VL + PrEP

ART-VL + SW

ART-VL + AVI

PrEP + SW

PrEP + AVI

 SAFER Study

$1709

$2039

$1638

$1659

$1242

 High Intensity (Study-level) with Real-world Prices (Scenario 1)

$517

$812

$444

$771

$408

 Target Intensity, Incremental Cost Added to CP (Scenario 2)

$483

$695

$328

$563

$291

 Target Intensity, Incremental Cost Added to SOC (Scenario 3)

$166

$450

$156

$387

$114

  1. ART-VL = Antiretroviral therapy with frequent viral load testing. AVI = Artificial vaginal insemination, at home. CP = Current practice. PrEP = Pre-exposure prophylaxis. SOC = Standard of Care. SW =Semen-washing
  2. aTotal strategy costs are for 6 months of conception attempts, plus a 2-month run-in period prior to attempting conception