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Table 3 SAFER Conception total cost per couple (2017 $US)

From: Estimated costs for the delivery of safer conception strategies for HIV-discordant couples in Zimbabwe: a cost analysis

Individual strategiesa ART-VL PrEP Semen-washing AVI  
 SAFER Study $1615 $1229 $1190 $769  
 High Intensity (Study-level) with Real-world Prices (Scenario 1) $431 $403 $563 $185  
 Target Intensity, Incremental Cost Added to CP (Scenario 2) $302 $266 $360 $73  
 Target Intensity, Incremental Cost Added to SOC (Scenario 3) $132 $88 $356 $62  
Strategy combinationsa ART-VL + PrEP ART-VL + SW ART-VL + AVI PrEP + SW PrEP + AVI
 SAFER Study $1709 $2039 $1638 $1659 $1242
 High Intensity (Study-level) with Real-world Prices (Scenario 1) $517 $812 $444 $771 $408
 Target Intensity, Incremental Cost Added to CP (Scenario 2) $483 $695 $328 $563 $291
 Target Intensity, Incremental Cost Added to SOC (Scenario 3) $166 $450 $156 $387 $114
  1. ART-VL = Antiretroviral therapy with frequent viral load testing. AVI = Artificial vaginal insemination, at home. CP = Current practice. PrEP = Pre-exposure prophylaxis. SOC = Standard of Care. SW =Semen-washing
  2. aTotal strategy costs are for 6 months of conception attempts, plus a 2-month run-in period prior to attempting conception