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Table 2 Requirements for breast cancer pathologies depending on the tier according to Sayed S. et al. [9], and Fleming KA et al. [11]

From: Breast cancer pathology services in sub-Saharan Africa: a survey within population-based cancer registries

 

Tier 21

Tier 3/ Tier 4 (Includes Tier 2 Capabilities)2,3

Population served

50,000–200,000

3–6 million

Staff

1 general pathologist, 6 laboratory technicians and pathology assistants

4 pathologists, 2 clinical scientists, 20 technicians and pathology assistants

Communication infrastructure

Paper, electronic, or (preferred) laboratory information system

Electronic or laboratory information system

Diagnostic

Anatomic pathology: FNAC, tissue biopsies, and surgical excisions-processing, H&E stain, and interpretation

Anatomic pathology: special stains, including immunohistochemistry

Public health

Report to other registries

Hospital-based registry/ population-based registry

Accreditation

Progressing towards accreditation, such as SLIPTA

National or international accreditation, such as ISO 15189 or other

Equipment

FNAC and biopsy fixation, microscope, tissue processor, microtome for anatomic pathology, refrigerator

Automated tissue processor, immunohistochemistry station, freezer

  1. 1 Tier 2: Laboratories in district hospitals that receive specimens from their own patients and receive referrals from tier 1 facilities
  2. 2 Tier 3: Laboratories in regional or provincial hospitals that receive specimens from their own patients and receive referrals from tier 1 and 2 facilities
  3. 3 Tier 4: Laboratories in national or teaching hospitals that receive specimens from their own patients and receive referrals from tier 1, 2 and 3 facilities
  4. Abbreviations: FNAC Fine-needle aspiration cytology, H&E Hematoxylin and Eosin, ER Estrogen, PR Progesterone, SLIPTA Stepwise Laboratory Quality Improvement Process Towards Accreditation