Theory-driven development of a medication adherence intervention delivered by eHealth and transplant team in allogeneic stem cell transplantation: the SMILe implementation science project

Ribaut, Janette; Leppla, Lynn; Teynor, Alexandra; Valenta, Sabine; Dobbels, Fabienne; Zullig, Leah L.; De Geest, Sabina

doi:10.1186/s12913-020-05636-1

Table 7 Applying the APEASE criteria to select useful BCTs in relation to COM-B and TDF

From: Theory-driven development of a medication adherence intervention delivered by eHealth and transplant team in allogeneic stem cell transplantation: the SMILe implementation science project

COM-B		TDF	Intervention function	Potential BCTs	Affordability	Practicability	(Cost-) Effectiveness	Acceptability	(Side-effects) / Safety	Equity	Does the BCT meet the APEASE criteria?
Capability	Physical	Physical skills	Enablement	1.4. Action planning (what to do when nausea)	+	+	++	+	++	++	yes
	Physical	Physical skills	Enablement	11.1. Pharmacological support	±	+	++	++	+	++	yes
	Psychological	Knowledge; Behavioral regulation; Memory, attention and decision processes; Cognitive and interpersonal skills	Education Training Enablement	5.1. Information about health consequences	++	++	++	++	++	++	yes
				2.7. Feedback on outcomes of the behavior	+	+	+	++	++	++	yes
				8.3. Habit formation (at real opportunities)	+	+	+	+	++	++	yes
				8.4. Habit reversal (at real opportunities)	±	+	±	±	±	±	no
				1.1. Goal setting	+	+	+	+	++	++	yes
				1.4. Action planning	+	+	+	++	++	++	yes
				1.6. Discrepancy between current behavior & goal	+	+	+	±	+	++	yes
				1.2. Problem solving including coping planning	+	+	+	++	++	++	yes
Opportunity	Physical	Context and resources	Enablement Training	12.5. Adding objects to the environment	+	+	++	+	++	++	yes
				7.1. Prompts/cues	++	++	++	+	+	++	yes
				12.1. Restructuring of the physical environment	–	–	±	–	±	+	no
				4.1. Instruction on how to perform behavior	++	++	++	++	++	++	yes
	Social	Social influence	Training Persuasion Enablement	2.2. Feedback on behavior	++	++	++	++	++	++	yes
				2.3. Self-monitoring of behavior	++	++	++	+	++	++	yes
				6.1. Demonstration of behavior	+	+	+	+	++	+	yes
				3.1.-3.3. Emotional, practical & unspecified social support	+	+	++	+	+	+	yes
Motivation	Automatic	Emotion	Persuasion	15.3. Focus on past success	+	+	++	++	++	++	yes
		Emotion	Enablement	11.2. Reduce negative emotions	±	±	±	++	++	++	no
		Reinforcement	Training	8.1. Behavioral practice / rehearsal	++	+	++	++	++	++	yes
		Reinforcement	Training	15.4. Self-talk	++	++	++	+	++	++	yes
	Reflective	Intentions; Beliefs about consequences / capabilities; Goals; Optimism; Social role & identity	Persuasion Enablement Training	9.1. Credible source	+	+	+	+	++	++	yes
				16.2. Imaginary reward	++	+	++	+	++	++	yes
				9.2. Pros & Cons	+	+	++	+	++	+	yes
				15.1. Verbal persuasion about capability	+	+	+	+	++	++	yes

(++ very promising) (+ promising) (± not promising but worth considering) (− unacceptable)

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