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Table 2 List of possible target behaviors

From: Theory-driven development of a medication adherence intervention delivered by eHealth and transplant team in allogeneic stem cell transplantation: the SMILe implementation science project

Possible target behavior

Impact of behavior change

Likelihood of change

Spillover effect

Measurement

Correct taking of immunosuppressants (i.e. persistently reducing number of missed immunosuppressants doses)

++

(↓ risk of GvHD [12])

++

++ (adherence to co-medication, no drug holidays)

++ [45]

Correct timing of immunosuppressants

++?

(↓ risk of GvHD? [46, 47])

+

++ (adherence to co-medication, no drug holidays)

++ [45]

Correct dosing of immunosuppressants

++

(↓ risk of GvHD [12])

+

+ (adherence to co-medication, no drug holidays)

± [45]

Performing no drug holidays

++

(↓ risk of GvHD [12])

++

+ (adherence to co-medication)

++ [45]

Following food considerations

++

(↓ risk of GvHD [12])

+

+ (considerations for co-medication)

- [45]

  1. EM Electronic monitoring; GvHD Graft-versus-Host Disease
  2. (++ very promising) (+ promising) (± not promising but worth considering) (− unacceptable)