Outcome | ΔC (95% CI) d | ΔE (95% CI) | ICER | CE plane | |||
---|---|---|---|---|---|---|---|
 |  |  |  | NE | SE | SW | NW |
Main analysis: Societal perspective | |||||||
 Quality of Life in Late-Stage Dementia (QUALID) score (11–55) | − 552 (− 2920; 1903) | −0.062 (− 0.40; 0.28) a,b | 8919 | 21% | 49% | 21% | 9% |
 Gain in Alzheimer Care Instrument (GAIN) score (0–40) | − 552 (− 2920; 1903) | 0.075 (− 0.20; 0.35) a,c | −7310 | 20% | 48%% | 22% | 10% |
 QALYs (0–1) | −552 (− 2920; 1903) | 0.0017 (− 0.059; 0.063) | −315,671 | 17% | 35% | 35% | 13% |
SA1: Unadjusted analysis | |||||||
 Quality of Life in Late-Stage Dementia (QUALID) score (11–55) | −552 (− 2920; 1903) | − 0.060 (− 0.40; 0.28)a | 9158 | 21% | 49% | 21% | 9% |
 Gain in Alzheimer Care Instrument (GAIN) score (0–40) | −552 (− 2920; 1903) | 0.033 (− 0.26; 0.32)a | −16,913 | 16% | 37% | 33% | 14% |
 QALYs (0–1) | −552 (− 2920; 1903) | 0.015 (− 0.058; 0.088) | − 36,774 | 20% | 46% | 24% | 10% |
SA 2: Healthcare perspective | |||||||
 Quality of Life in Late-Stage Dementia (QUALID) score (11–55) | − 548 (− 2805; 1927) | − 0.062 (− 0.40; 0.28) a,b | 8861 | 19% | 50% | 21% | 9% |
 Gain in Alzheimer Care Instrument (GAIN) score (0–40) | − 548 (− 2805; 1927) | 0.075 (− 0.20; 0.35) a,c | − 7263 | 19% | 49% | 23% | 9% |
 QALYs (0–1) | − 548 (− 2805; 1927) | 0.0017 (− 0.059; 0.063) | − 313,640 | 16% | 36% | 35% | 13% |
SA 3: Ignore clustering of data | |||||||
 Quality of Life in Late-Stage Dementia (QUALID) score (11–55) | − 311 (− 3340; 2227) | 0.15 (− 0.27; 0.47) a,b | − 2065 | 7% | 10% | 49% | 34% |
 Gain in Alzheimer Care Instrument (GAIN) score (0–40) | − 311 (− 3340; 2227) | 0.18 (− 0.12; 0.48) a,c | − 1714 | 37% | 51% | 7% | 5% |
 QALYs (0–1) | − 311 (− 3340; 2227) | 0.0018 (− 0.058; 0.062) | − 169,209 | 22% | 32% | 26% | 20% |
SA 4: Complete-case analysis | |||||||
 Quality of Life in Late-Stage Dementia (QUALID) score (11–55) | 214 (− 7863; 5630) | − 0.20 (− 0.53; 0.12) a,b | − 1059 | 46% | 45% | 5% | 4% |
 Gain in Alzheimer Care Instrument (GAIN) score (0–40) | 214 (− 7863; 5630) | − 0.15 (− 0.44; 0.15) a,c | − 1469 | 2% | 13% | 37% | 48% |
 QALYs (0–1) | 214 (− 7863; 5630) | 0.026 (− 0.12; 0.072) | − 8118 | 13% | 13% | 37% | 37% |