- The table displays the mean doses of dispensed opioids analgesics among patients who discontinued OAT. Patients’ opioid dispensations were analyzed in three periods according to the OAT disconatinuation date: 180–90 days before, 90 days before, and 90 days after the discontinuation date. All doses of dispensed opioid analgesics were summarized in each period and converted to OMEQ. The mean, median, 25 percentile and 75 percentile were calculated for the three periods. For those who were dispensed opioid analgesics in the periods before and after the discontinuation date, we have used a paired t-test for calculating differences in dispensed doses of the opioid analgesics.
- CI Confidence interval, Df Degree of freedom, OAT Opioid agonist therapy, OMEQ Oral morphine equivalents.
- 1) The change in opioid analgesic dose when comparing dispensed doses before discontinuation with dispensed doses after discontinuation
- 2) Paired t-test of the mean daily dose at the 90 days after discontinuation compared with the mean daily dose at baseline (180 to 90 days before discontinuation). Df = 37
- 3) Paired t-test of the mean daily dose at the last 90 days before discontinuation compared with the mean daily dose at the 90 days after discontinuation. Df = 12
- 4) Paired t-test of the mean daily dose at the 90 days after discontinuation compared with the mean daily dose at baseline (180 to 90 days before discontinuation). Df = 8
