From: Patient-relevant outcomes: what are we talking about? A scoping review to improve conceptual clarity
Authors | Objective/ motivation of article | Type of article/ study | Terms used synonymously | Indicator disease/ intervention | Outcomes considered patient-relevant [instrument, if applicable] |
---|---|---|---|---|---|
Agarwal et al. 2017 [40] | Examination to what extent Cochrane and non-Cochrane reviews report absolute effects for patient-important outcomes in the abstract | Systematic review | 1 term: - patient-important outcome | Generic | - mortality - morbidity - symptoms - quality of life - functional status |
Cao et al. 2014 [41] | Comparison of the efficacy of two commonly used Chinese patent medicines for patients with angina pectoris | Study protocol for a randomized controlled trial | 1 term: - patient-important outcome | Angina pectoris | - short of breath - fatigue - palpitations - sweating |
Cleveringa et al. 2010 [42] | Determination of the effects of the Diabetes Care Protocol on patient-important outcomes Note: When applying the Diabetes Care Protocol, routine diabetes care is delegated to a nurse, who uses a computerized decision support system to structure diabetes care and set targets | Cluster-randomized trial | 1 term: - patient-important outcome | Type 2 diabetes | - diabetes-specific health status: psychological distress, barriers to activity, disinhibited eating [DHP-18] - general health status [SF-36, EQ-5D] - treatment satisfaction [DTSQ-status] - self-efficacy [DES-SF] |
Englund et al. 2001 [43] | Evaluation of long-term patient-relevant outcomes after removal of knee meniscus | Retrospective cohort study | 2 terms: - patient-relevant outcome - self-administered outcome measure | Meniscectomy | - general health status [SF-36] - knee-specific health status: pain, symptoms, activities of daily life, sports and recreation function, knee-related quality of life [KOOS] |
Gandhi et al. 2008 [3] | Determination to what extent registered randomized controlled trials among patients with diabetes plan to assess patient-important outcomes | Systematic review | 1 term: - patient-important outcome | Diabetes | - mortality - quality of life - major morbid events - minor morbid events - pain - functional status |
Griffith et al. 2019 [44] | Determination how different disease frameworks impact the prevalence of multimorbidity and its association with patient-important outcomes | Baseline analysis of a population-based cohort study | 2 terms: - patient-important functional outcome - patient-important outcome | Generic; community-living adults aged 45 to 85 years | - functional disability [OARS questionnaire] - social participation restriction - self-rated physical health - self-rated mental health |
Nilsdotter et al. 2003 [45] | Evaluation of long-term patient-relevant outcomes after unilateral total hip replacement for osteoarthritis | Case-control-study | 1 term: - patient relevant outcome | Unilateral total hip replacement for osteoarthritis | - general health status [SF-36] - knee-specific health status: pain, stiffness, physical function [WOMAC] - postoperative complications - general comorbidity - musculoskeletal comorbidity: need of walking assistance, walking distance, pain, need for analgesics, joint replacement in contralateral hip or in knee, fractures - patient satisfaction |
Paradowski et al. 2004 [46] | Assessment of variation in knee pain, function, and quality of life over two years after removal of knee meniscus in patients with and and without radiographic knee osteoarthritis | Prospective follow-up study | 1 term: - patient-relevant outcome | Meniscectomy | - knee-specific health status: pain, symptoms, activities of daily life, sports and recreation function, knee-related quality of life [KOOS] |
Porat et al. 2004 [47] | Identification of the consequences of an anterior cruciate ligament tear 14 years after injury in a cohort of male soccer players regarding radiographic knee osteoarthritis and patient-relevant outcomes | Prospective cohort study | 1 term: - patient relevant outcome | Anterior cruciate ligament tear | - general health status [SF-36] - knee-specific health status: pain, symptoms, activities of daily life, sports and recreation function, knee-related quality of life, functional disability [KOOS, Lysholm Knee Score] |
Ramar et al. 2017 [48] | Synthesis of the literature with regard to models of care targeting patient-important outcomes for maintenance dialysis patients focusing on hospitalization and mortality | Systematic review & meta-analysis | 2 terms: - patient-important outcome - patient outcome | Maintenance dialysis care | - mortality - hospitalization |
Schnabel et al. 2014 [49] | Comparison of the analgesic efficacy and safety of ultrasound and nerve stimulator guided peripheral nerve catheters for postoperative pain therapy | Retrospective database analysis | 4 terms: - patient-relevant target parameter - patient-related outcome - patient-relevant parameter [German: Patienten-relevanter Parameter] - patient-relevant efficacy parameter [German: Patienten-relevanter Effektivitätsparameter] | Peripheral nerve catheters for pain therapy | - postoperative pain - postoperative need for additional opioids - cumulative local anesthetic consumption - puncture-associated complications - postoperative catheter-related complications |
Stallmach et al. 2015 [50] | Examination of possible improvements in the clinical situation of patients with inflammatory bowel disease in Germany, focusing on patient-relevant endpoints | Secondary data analysis | 1 term: - patient-relevant endpoint | Inflammatory bowel diseases | - number of stationary treatments per year (cases) - average residence time - number of operations - inability to work - premature mortality |
W-Dahl et al. 2005 [51] | Evaluation of the patient-relevant outcomes pain, function, and quality of life during two years in patients operated on for knee osteoarthritis with tibial osteotomy | Prospective follow-up study | 1 term: - patient-relevant outcome | Tibial osteotomy for uni-compartmental knee osteoarthritis | - knee-specific health status: pain, symptoms, activities of daily life, sports and recreation function, knee-related quality of life [KOOS] - complications, e.g., delayed healing, deep venous thrombosis |