- a) Extent participants were randomly allocated to groups how this was concealed throughout enrolment (Random sequence generation, Allocation concealment)
- b and c) Extent to which the researchers/participants were blinded to the group they are allocated to.
- d) Assessment of the completeness of outcome data
- e) Extent the outcome assessors were blinded to the intervention/control
- f) Measurement of how selective researchers have been when reporting outcomes (Selective reporting)
- g) Any forms of bias not covered in the five domains (Research quality)