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Table 1 Management and complication costs used in the CDM

From: Improving management of glycaemic control in people with T2DM in primary care: estimation of the impact on the clinical complications and associated costs

Management costs Cost (€) Source
Statins (Atorvastina 20 MG 28 comprimidos) 120.14 https://botplusweb.portalfarma.com/botplus.aspx Botplus 2015
Aspirin (Adiro 100 mg 30 comprimidos) 88.27 https://botplusweb.portalfarma.com/botplus.aspx Botplus 2015
ACE inhibitor (Enalapril 20 MG 28 comprimidos) 21.00 https://botplusweb.portalfarma.com/botplus.aspx Botplus 2015
Annual Screening for microalbuminurea 50.83 eSalud 2015 (official tariff)
Annual screening gross renal protenuira 203.44 eSalud 2015 (official tariff)
Stopping ACEs due to side effects 54.08 [21] Fonseca 2013
Annual eye screening 55.27 eSalud 2015 (official tariff)
Foot screening program 23.69 eSalud 2015 (official tariff)
Non-standard ulcer treat (eg. Regranex)  
Anti-depression treatment 288.05 [22] Salvador-Carulla 2009
Screening for depression eSalud 2015 (official tariff)
Direct costs CVD complications Cost (€) Source
Myocardial infarction 1st year average 5282.63 [23] Abad 2015
Myocardial infarction 1st year fatal 4566.21 [23] Abad 2015
Myocardial infarction 1st year non-fatal 5383.13 [23] Abad 2015
Myocardial infarction 2nd + years 860.43 [23] Abad 2015
Angina 1st year 2373.60 [23] Abad 2015
Angina 2nd + years 860.43 [23] Abad 2015
Congestive heart failure 1st year average 3564.34 [23] Abad 2015
Congestive heart failure 1st year fatal 4566.21 [23] Abad 2015
Congestive heart failure 1st year non-fatal 3505.02 [23] Abad 2015
Congestive heart failure 2nd plus years 3554.47 [23] Abad 2015
Stroke 1st year non-fatal 6658.42 [23] Abad 2015
Stroke 2nd + years 3595.02 [23] Abad 2015
Stroke death within 30 days 4566.21 [23] Abad 2015
Peripheral vascular disease 1st year 2373.60 [23] Abad 2015
Peripheral vascular disease 2nd + years 860.43 [23] Abad 2015
Direct costs renal complications Cost (€) Source
Haemodialysis 1st year 47,069.14 [24] Villa 2011
Haemodialysis 2+ years 43,997.16 [24] Villa 2011
Peritoneal dialysis 1st year 32,022.17 [24] Villa 2011
Peritoneal dialysis 2+ years 29,927.06 [24] Villa 2011
Renal transplant costs 1st year 51,677.66 [24] Villa 2011
Renal transplant 2+ years 7280.71 [24] Villa 2011
Direct costs acute events Cost (€) Source
Major hypoglycaemic event 1038.23 [25] Hammer 2009
Minor hypoglycaemic event 59.07 [25] Hammer 2009
Lactic acid event 3446.53 Ministry of Health 2012
Edema onset (adverse event) 5225.52 Ministry of Health 2012
Edema follow-up (adverse event)  
Direct costs acute events Cost (€) Source
Laser treatment 126.84 eSalud 2015 (official tariff)
Cataract operation 1006.63 eSalud 2015 (official tariff)
Following cataract operation 52.32 Tarifas CCAA 2008.
Blindness - year of onset 1875.14 [23] Abad 2015
Blindness - following years 805.05 [23] Abad 2015
Direct costs acute events Cost (€) Source
Neuropathy, 1st year 4653.06 [26] Rodríguez 2011
Neuropathy, 2nd + years 4653.06 [26] Rodríguez 2011
Amputation (event based) 3644.47 [23] Abad 2015
Amputation Prosthesis (event based) 3712.05 Estimation
Gangrene treatment 10,131.19 eSalud 2015 (official tariff)
After healed ulcer  
Infected ulcer 5042.78 eSalud 2015 (official tariff)
Standard uninfected ulcer 1120.96 eSalud 2015 (official tariff)
Healed ulcer history of amputation