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Table 3 Segmented regression analysis for vascular protective medication and comparator coverage 2010 to 2016, EMR cohort

From: Impact of the diabetes Canada guideline dissemination strategy on dispensed vascular protective medications for older patients in Ontario, Canada: a linked EMR and administrative data study

Statin

Variable

Estimate

SE

Pvalue

Baseline prescription rate

63.26

0.52

<.0001

Pre-intervention slope

0.11

0.06

0.11

Change at guideline (2013Q2)

− 0.90

0.61

0.15

Slope change

−0.03

0.09

0.70

ACEi or ARB

 Baseline prescription rate

63.99

0.43

<.0001

 Pre-intervention slope

−0.15

0.05

0.01

 Change at guideline (2013Q2)

−0.46

0.51

0.38

 Slope change

0.03

0.07

0.64

Antiplatelet

 Baseline prescription rate

9.54

0.15

<.0001

 Pre-intervention slope

−0.12

0.02

<.0001

 Change at guideline (2013Q2)

0.13

0.17

0.5

 Slope change

0.001

0.03

0.97

PPI

 Baseline prescription rate

21.84

0.44

<.0001

 Pre-intervention slope

0.23

0.05

<.0001

 Change at guideline (2013Q2)

0.27

0.43

0.54

 Slope change

−0.07

0.08

0.36

  1. SE standard error
  2. ACEi angiotensin-converting enzyme inhibitor; ARB angiotensin receptor blockers; PPI proton pump inhibitor