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Table 3 Multivariable logistic regression analysis of HA administration for each of the 3 disease groups

From: Establishing a hospital transfusion management system promotes appropriate clinical use of human albumin in Japan: a nationwide retrospective study

 

Bleeding

Sepsis

Burn injury

OR (95% CI)

OR (95% CI)

OR (95% CI)

Age

 15–39

Ref.

Ref.

Ref.

 40–69

0.78 (0.68–0.88)

1.85 (1.66–2.06)

2.31 (1.82–2.95)

  ≥ 70

1.22 (1.05–1.42)

1.45 (1.30–1.61)

5.98 (4.68–7.63)

JCS

 0 (alert)

Ref.

Ref.

Ref.

 1–3 (delirious)

3.96 (3.41–4.59)

1.13 (1.08–1.17)

1.97 (1.65–2.35)

 10–30 (somnolent)

6.41 (5.22–7.86)

1.36 (1.29–1.43)

2.90 (2.08–4.05)

 100–300 (comatose)

10.52 (8.66–12.79)

1.78 (1.69–1.88)

4.23 (3.16–5.66)

CCI

 0

Ref.

Ref.

Ref.

 1

1.12 (0.92–1.36)

0.92 (0.88–0.95)

1.51 (1.27–1.81)

 2

1.13 (0.77–1.64)

0.93 (0.89–0.97)

1.44 (1.08–1.92)

  ≥ 3

1.50 (0.88–2.54)

0.85 (0.81–0.90)

1.32 (0.85–2.05)

Burn index

  < 10

  

Ref.

  ≥ 10

  

12.25 (10.59–14.17)

Mechanical ventilation

 Not performed

Ref.

Ref.

Ref.

 Performed

12.97 (6.77–24.85)

5.50 (5.25–5.76)

10.00 (6.78–14.75)

Hospital type

 Non-academic

Ref.

Ref.

Ref.

 Academic

1.54 (1.21–1.94)

2.04 (1.69–2.46)

1.84 (1.41–2.41)

Hospital bed size

  < 200

Ref.

Ref.

Ref.

 200–499

1.64 (0.85–3.16)

1.50 (1.25–1.81)

2.98 (1.31–6.75)

  ≥ 500

2.22 (1.15–4.27)

1.89 (1.54–2.32)

5.01 (2.21–11.31)

Hospital transfusion management system

 HTD not introducing GPC

Ref.

Ref.

Ref.

 HTD introducing GPC

0.70 (0.59–0.83)

0.75 (0.69–0.81)

0.71 (0.58–0.87)

 Non-HTD

0.81 (0.52–1.24)

1.12 (0.95–1.32)

0.65 (0.38–1.12)

  1. CCI Charlson comorbidity index; CI confidence intervals; GPC good practice criteria of blood products; HA human albumin; HTD hospital transfusion department; OR odds ratio; Ref reference