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Table 2 Temporal trends in the number of hospitals and patient outcomes

From: Establishing a hospital transfusion management system promotes appropriate clinical use of human albumin in Japan: a nationwide retrospective study

 

FY 2012

FY 2013

FY 2014

FY 2015

FY 2016

P value

Hospital characteristics (Total No.: 682)

 HTD introducing GPC

418

418

454

454

451

 

 HTD not introducing GPC

187

187

172

172

177

 

 Non-HTD

77

77

56

56

54

 

Patient characteristics

  “Bleeding” total patients No.

3928

4331

4487

4357

4474

 

  HA administration No.

419

432

414

367

390

 

   Prop. (%)

10.7

10.0

9.2

8.4

8.7

0.002a

  In-hospital death No.

54

57

48

62

62

 

   Mortality rate (%)

1.4

1.3

1.1

1.4

1.4

0.60a

  Average hospital LOS (day)

19.3

19.1

17.7

16.3

16.5

0.037†

  “Sepsis” total patients No.

18,406

19,973

23,301

24,452

24,330

 

  HA administration No.

4209

4413

4933

4937

5028

 

   Prop. (%)

22.9

22.1

21.2

20.2

20.7

< 0.001a

  In-hospital death No.

4052

4008

4515

4425

4543

 

   Mortality rate (%)

22.0

20.1

19.4

18.1

18.7

< 0.001a

  Average hospital LOS (day)

30.6

30.3

28.1

27.6

27.5

< 0.001†

  “Burn injury” total patients No.

1598

1675

1647

1531

1363

 

  HA administration No.

410

446

406

356

313

 

   Prop. (%)

25.7

26.6

24.7

23.3

23.0

0.089a

  In-hospital death No.

122

142

132

121

87

 

   Mortality rate (%)

7.6

8.5

8.0

7.9

6.4

0.28a

  Average hospital LOS (day)

36.2

35.4

33.6

33.7

33.2

0.037†

  1. Note: Mortality rate was estimated by dividing “in-hospital death No.” by “Total patient No.”. The results of the statistical analysis of patient outcomes were estimated for each of the 3 patient groups across all hospitals. aObtained by the Cochran-Armitage test; †Obtained by Spearman’s rank correlation. HA human albumin; FY fiscal year (begin on 1 April of the year, and end on 31 March of the next year); HTD hospital transfusion department; GPC good practice criteria of blood products; Prop proportion