Study ID | Country | Design (groups) and n (number randomised) | Population, i) Age (yrs) mean (SD); ii) Baseline prescribed medications mean (SD) | Home visit frequency (INT group only) | Components of home visit | Comparator | Primary Outcome |
---|---|---|---|---|---|---|---|
UK | RCT (2 INT, 1 C) n = 222 | Post-discharge (after emergency admission), Age: INT 84(−); C 82(−) Meds: INT 5 (2); C 5 (2) | Group 1: No counselling Group 2: With counselling 5 visits (2w,1 m,3 m,1y) | Medication knowledge and compliance assessment (Group 1). As above PLUS education on medication management and storage, and advice on improving compliance (Group 2). | Usual care | Medication management | |
UK | RCT (1 INT, 1 C) n = 822 The HOMER trial | Post-discharge (after emergency admission), Age: INT 85.5 (4); C 85.5 (4) Meds: INT 6 (3); 6 (2) | 2 visits (within 2 weeks, 6-8 weeks) | Educate, remove out of date drugs, assessed adherence and advised on medication issues. Liaised with GP and local pharmacist where needed | Usual care | Emergency hospital admissions | |
Holland 2007 [25] | UK | RCT (1 INT, 1 C) n = 339 | Post-discharge (after HF admission) Age: INT 77.6 (9); C 76.4 (9) Meds: INT 8 (3); C 8 (2) | 2 visits (within 2 weeks, 6–8 weeks) | Educate, remove out of drugs and lifestyle behaviours, and provided BHF leaflet. Liaised with GP and local CP where needed | Usual care | Emergency hospital admissions |
Jackson 2004 [28] | Australia | RCT (1 INT, 1 C) n = 128 | Post-discharge and initiated on warfarin Age:*INT 70(−); *C 72.5(−) Meds: INT 6(−); C 6(−) | 4 visits (2, 4, 6 and 8 days) | Education and counselling related to warfarin with booklet and info sheet provided. Post visit communication with GP | Usual care | Reduction in bleeding complications |
Lenaghan 2007 [33] | UK | RCT (1 INT, 1 C) n = 136 The POLYMED trial | Community Age: INT 84.1(−); C 84.5 (−) Meds: INT 7(−); C 7(−) | 2 visits (within 2 weeks, 6–8 weeks) | Medication review, educated the patient, removed out-of-date drugs, and assessed the need for an adherence aid. Post visit communications with GP | Usual care | Non elective hospital admissions |
Naunton 2003 [32] | Australia | RCT: 1 INT, 1 C n = 136 | Post-discharge with ≥2 chronic diseases Age: INT 74(−); C 74 (−) Meds: INT > 5(−); C > 5(−) | 2 visits (5 days, 3 months) | Medication review, optimise medication management, education and detect DRPs | Usual care | Unplanned hospital admissions at 90 days, & Death |
Olesen 2014 [26] | Denmark | RCT: 1 INT, 1 C n = 630 | Community Age: *INT 74(−);*C 74(−); Meds: INT 7(−); C 7(−) | 1 visit followed up by telephone calls at 3, 6 and 9 months | Medication review, counselling on medication, motivated adherence, provided leaflets. Contact with GP if serious issue. | Usual care | Medication adherence (Pill count) |
Peterson 2004 [29] | Australia | RCT (1 INT, 1 C) n = 94 | Post-discharge (after CV-related admission) and initiated on statins Age: INT 65.5 (11); C 63.5 (12) Meds:*8(−); *8(−) | 1 visit at 6 weeks, and monthly thereafter up to 6 months | Educated on the goals and proven benefits of lipid-lowering drug therapy, and appropriate lifestyle modifications. Assessed for DRPs and compliance checked | Usual care | Cholesterol levels |
Sidel 1990 [22] | USA | RCT (1 INT, 1 C) n = 284 | Community at high risk of medication issues Age: INT > 65(−); C > 65(−) Meds: INT NR; C NR | 2 visits over a 6–11 months with telephone follow-up as needed | Education on medication, remove out of date drugs, encourage communication with health providers if any issues arose. | Usual care | Medication management |
Triller 2007 [30] | USA | RCT (1 INT, 1 C) n = 144 | Post-discharge (after HF admission) Age: INT 81.3 (9); C 78.1 (11) Meds: INT NR; C NR | 3 visits over 3–4 weeks | Medication review, counselling on medication, healthy lifestyle advice. | Usual care | All cause hospital admissions, HF- related admissions |
Tuttle 2018 [31] | USA | RCT (1 INT, 1C) n = 159 | Post-discharge (after CKD admission) Age: INT 70 (12); C 69 (10) Meds: ALL 13 (5) | 1 visit within 7 days | Comprehensive medication review, medication action plan, and a personal medication list. Advice on proper medicine use and avoidance of contraindicated drugs. Post visit contact with GP if needed | Usual care | Acute care utilisation (hospital admissions and ED/ urgent care centre visits |
Vuong 2008 [27] | Australia | RCT (1 INT, 1 C) n = 316 | Post-discharge Age: INT 74.4 (11); C 69.3 (12); Meds: INT 11 (4); C 10 (4) | 1 visit within 5 days | Medication reviews, education and information on medications, removal of our-of-date drugs. Post visit contact with GP and CP if needed. | Usual care | Medication adherence Medication knowledge |