Developing an adapted Charlson comorbidity index for ischemic stroke outcome studies

Table 2 Comorbidity weights derived from the ischemic stroke test cohort (April 1, 2012 to March 31, 2013) compared with weights of the original Charlson comorbidity index [11]

Ischemic stroke weight (ISCCI)	Comorbid condition	Charlson Weight
2	Myocardial infarction	1
2	Congestive heart failure	1
0	Peripheral vascular disease	1
1	Cerebrovascular disease	1
2	Dementia	1
1	Chronic obstructive pulmonary disease	1
2	Rheumatologic disease	1
–	Peptic ulcer disease	1
–	Mild liver disease	1
–	Diabetes without chronic complications	1
1	Diabetes with chronic complications	2
1	Hemiplegia or paraplegia	2
0	Renal disease	2
2	Primary Cancer (any malignancy)	2
–	Moderate or severe liver disease	3
5	Metastatic solid tumor	6
–	AIDS/HIV	6
19	Maximum comorbidity score	29

- Not included in the Cox proportional hazard model as did not achieve threshold in bivariate analysis
Calculation of the maximum score is based on a hierarchy where diabetes with complications supersedes diabetes without complications; moderate or severe liver disease supersedes mild liver disease; and metastatic solid tumor supersedes any malignancy

ISSN: 1472-6963