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Table 6 Sensitivity analysis for the costs of warfarin therapy (2018 prices)

From: Modeling patients’ time, travel, and monitoring costs in anticoagulation management: societal savings achievable with the shift from warfarin to direct oral anticoagulants

Annual cost EUR (share % from the total cost)Number of annual INR measurements:Number of annual INR measurements:Number of annual INR measurements:Number of annual INR measurements:
5101520
The value of leisure time (%/gross wage per hour):The value of leisure time (%/gross wage per hour):The value of leisure time (%/gross wage per hour):The value of leisure time (%/gross wage per hour):
203550203550203550203550
Total cost of warfarin therapy:1,291,770 (100)1,324,700 (100)1,357,630 (100)2,372,160 (100)2,438,030 (100)2,503,890 (100)3,452,560 (100)3,551,360 (100)3,650,150 (100)4,532,950 (100)4,664,690 (100)4,796,410 (100)
 Direct costs1,009,370 (78.1)1,009,370 (76.2)1,009,370 (74.3)1,807,370 (76.2)1,807,370 (74.1)1,807,370 (72.2)2,605,370 (75.5)2,605,370 (73.4)2,605,370 (71.4)3,403,370 (75.1)3,403,370 (73.0)3,403,370 (71.0)
  INR measurements and monitoring798,000798,000798,0001,596,0001,596,0001,596,0002,394,0002,394,0002,394,0003,192,0003,192,0003,192,000
  Warfarin medication211,370211,370211,370211,370211,370211,370211,370211,370211,370211,370211,370211,370
 Indirect costs282,400 (21.9)315,330 (23.8)348,260 (25.7)564,790
(23.8)
630,660 (25.9)696,520 (27.8)847,190 (24.5)945,990 (26.6)1,044,780 (28.6)1,129,580 (24.9)1,261,320 (27.0)1,393,040 (29.0)
  Time costs of INR measurements and monitoring35,64057,04078,44071,270114,080156,880106,910171,120235,320142,550228,160313,770
  Travel costs224,700224,700224,700449,410449,410449,410674,110674,110674,110898,810898,810898,810
  Travel time costs22,06033,59045,12044,11067,17090,23066,170100,760135,35088,220134,350180,460