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Table 5 Costs and benefits (USD/woman) of various models from societal and government perspective when cost of NIPS is $416.86 (13,000 THB)

From: Fetal Down syndrome screening models for developing countries; Part II: Cost-benefit analysis

Strategies

Societal Perspective

Government Perspective

Cost of screening and prenatal diagnosis

(1)

Cost saved by avoiding DS births

(2)

WTP

(3)

Benefit-cost difference

(4)

Benefit- cost ratio

(5)

Cost of screening and prenatal diagnosis

(1)

Cost saved by avoiding DS births

(2)

WTP

(3)

Benefit-cost difference

(4)

Benefit- cost ratio

(5)

1. No screening

0

0

0

0

0

0

0

0

0

0

2. Maternal age alone

80.0

184.5

0.7

105.2

2.32

18.1

32.7

0.7

15.3

1.84

3. STS alone

164.4

571.9

2.3

409.7

3.49

51.9

101.3

2.3

51.6

1.99

4. Independent screen (I-S)

150.9

597.1

2.4

448.6

3.97

47.0

105.7

2.4

61.1

2.30

5.C-S plus STS

149.4

607.6

2.4

460.6

4.08

48.8

107.6

2.4

61.2

2.26

6. Maternal age with NIPS

62.2

180.1

0.7

118.7

2.91

52.4

31.9

0.7

−19.8

0.62

7. STS alone with NIPS

146.4

551.9

2.2

407.7

3.78

74.0

97.7

2.2

25.9

1.35

8. I-S with NIPS

137.1

584.9

2.3

450.1

4.28

65.8

103.6

2.3

40.1

1.61

9. C-S plus STS with NIPS

139.4

581.5

2.3

444.4

4.19

60.8

103.0

2.3

44.5

1.73

10. Universal NIPS

494.8

719.4

2.8

227.4

1.46

416.2

127.4

2.8

− 286.0

0.31

  1. Benefit-cost difference = [(2 + 3) any situation – (2 + 3) situation 1] – [1 any situation – 1 situation 1]
  2. Benefit-cost ratio = [(2 + 3) any situation – (2 + 3) situation 1] / [1 any situation – 1 situation 1]