From: Fetal Down syndrome screening models for developing countries; Part II: Cost-benefit analysis
Strategies | Societal Perspective | Government Perspective | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Cost of screening and prenatal diagnosis (1) | Cost saved by avoiding DS births (2) | WTP (3) | Benefit-cost difference (4) | Benefit- cost ratio (5) | Cost of screening and prenatal diagnosis (1) | Cost saved by avoiding DS births (2) | WTP (3) | Benefit-cost difference (4) | Benefit- cost ratio (5) | |
1. No screening | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2. Maternal age alone | 80.0 | 184.5 | 0.7 | 105.2 | 2.32 | 18.1 | 32.7 | 0.7 | 15.3 | 1.84 |
3. STS alone | 164.4 | 571.9 | 2.3 | 409.7 | 3.49 | 51.9 | 101.3 | 2.3 | 51.6 | 1.99 |
4. Independent screen (I-S) | 150.9 | 597.1 | 2.4 | 448.6 | 3.97 | 47.0 | 105.7 | 2.4 | 61.1 | 2.30 |
5.C-S plus STS | 149.4 | 607.6 | 2.4 | 460.6 | 4.08 | 48.8 | 107.6 | 2.4 | 61.2 | 2.26 |
6. Maternal age with NIPS | 62.2 | 180.1 | 0.7 | 118.7 | 2.91 | 52.4 | 31.9 | 0.7 | −19.8 | 0.62 |
7. STS alone with NIPS | 146.4 | 551.9 | 2.2 | 407.7 | 3.78 | 74.0 | 97.7 | 2.2 | 25.9 | 1.35 |
8. I-S with NIPS | 137.1 | 584.9 | 2.3 | 450.1 | 4.28 | 65.8 | 103.6 | 2.3 | 40.1 | 1.61 |
9. C-S plus STS with NIPS | 139.4 | 581.5 | 2.3 | 444.4 | 4.19 | 60.8 | 103.0 | 2.3 | 44.5 | 1.73 |
10. Universal NIPS | 494.8 | 719.4 | 2.8 | 227.4 | 1.46 | 416.2 | 127.4 | 2.8 | − 286.0 | 0.31 |