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Table 1 Probabilities of the events used in the simulations [8]

From: Fetal Down syndrome screening models for developing countries; Part II: Cost-benefit analysis

Variables

Distri-bution

Mean

 Prevalence of women attending antenatal care in the first trimester

normal

0.7080

 Prevalence of DS at 16 weeks of gestation in women of < 35 years of age

beta

0.0016

 Prevalence of DS at 16 weeks of gestation in women of ≥ 35 years of age

beta

0.0057

 Prevalence of DS at 16 weeks of gestation in women of all age

beta

0.0018

Prevalence of DS in women of all age

beta

0.0018

 MSS uptake among women of all age

beta

0.9557

 Amniocetesis uptake among women of all age

beta

0.9245

 Spontaneous abortion of DS fetuses at 10 weeks of gestation in women of all age

beta

0.2713

 Spontaneous abortion of DS fetuses at 16 weeks of gestation in women of all ages

beta

0.2175

Spontaneous abortion of DS fetuses in women of all age

beta

0.2920

 Termination of pregnancy in case of +ve amniocentesis

normal

0.9500

 Amniocentesis-related fetal loss

beta

0.0050

 NIPS uptake (assumption for free of charge)

beta

0.9900