Outcome | Estimate |
---|---|
Mean time to treatment reduction (SD) | 42 min (SD 63) |
Changes in population mRS (n) * | |
0 | 15 |
1 | 18 |
2 | -4 |
3 | -10 |
4 | −8 |
5 | −8 |
6 | −4 |
Marginal Lifetime QALY gains across English pop. | 213 (95% CI 28, 447) |
Marginal Lifetime costs to NHS England | -£2,870,000 (95% CI -£7,946,000 to £2,051,000) |
Net Benefit at £20,000 per QALYb | £7,123,000 (95% CI £1,039,000 to £13,666,000) |
Net Benefit at £25,000 per QALYb | £8,187,000 (95% CI £1,609,000 to £ 15,684,000) |
Net Benefit at £30,000 per QALYb | £ 9,250,000 (95% CI £1,983,000 to £ 17,532,000) |
Budget Impact Analysis | |
Year 1 | -£981,000(95% CI -£2,067,000 to £218,000) |
Years 2 to 5 (discounted) | - £1,186,000 (95% CI -£3,587,000 to £1,187,000) |
Sensitivity Analyses expressed as change in Net Benefit at £25,000 willingness to pay for QALY | |
Use of Ambulance Tariff | £20,000 |
1% increase in LAO incidence | £93,000 |
1% decrease in LAO incidence | -£72,000 |
Mean age at stroke −5 years (65) | £1,023,000 22 additional QALYs, additional savings of £473,000 |
Mean age at stroke + 5 years (75) | -£934,000 27 fewer QALYs, reduction in savings of £259,000 |