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Table 3 Combinations of comorbidities and prolonged length of stay

From: Multimorbidity and healthcare resource utilization in Switzerland: a multicentre cohort study

Combinations of comorbidities a OR (95% CI) b Interaction c Difference in median LOS (95% CI) d
Miscellaneous mental health disorders Mood disorders 11.28 (8.71;14.61) + 17.3 (16.5;18.3)
Diseases of white blood cells Hematological malignancy 10.95 (9.06;13.24) + 15.7 (15.1;16.8)
Chronic heart disease Chronic ulcer of skin 4.83 (3.77;6.17) + 7.8 (6.8;8.7)
Anxiety disorders Mood disorders 4.10 (3.06;5.49) 0 7.6 (6.4;8.8)
Chronic heart disease Diseases of white blood cells 3.92 (3.01;5.11) 0 8.0 (7.0;9.1)
Paralysis Solid malignancy 3.37 (2.54;4.47) 0 6.6 (5.5;7.8)
Chronic heart disease Liver disease 3.36 (2.76;4.08) + 6.2 (5.5;7.0)
Chronic kidney disease Chronic ulcer of skin 3.22 (2.40;4.31) 5.4 (4.2;6.5)
Chronic heart disease Hematological malignancy 3.21 (2.62;3.92) 0 5.2 (4.3;6.0)
Chronic kidney disease Hematological malignancy 3.16 (2.42;4.14) 0 4.3 (3.2;5.4)
Arthropathy and arthritis Mood disorders 3.10 (2.42;9.96) 5.7 (4.8;6.7)
Paralysis Other nervous system disorders 3.02 (2.40;3.78) 0 5.1 (4.2;6.0)
Miscellaneous mental health disorders Chronic heart disease 3.01 (2.30;3.93) 0 4.8 (3.8;5.9)
Dementia Mood disorders 2.95 (2.27;3;82) 5.6 (4.6;6.6)
Paralysis Epilepsy; convulsions 2.92 (2.28;3.75) 0 5.0 (4.0;6.0)
Other nervous system disorders Mood disorders 2.89 (2.28;3.66) 0 5.9 (5.0;6.9)
Chronic kidney disease Liver disease 2.89 (2.19;3.80) 0 4.9 (3.8;6.1)
Dementia Substance-related disorders 2.83 (2.13;3.75) 0 5.1 (3.9;6.2)
Other nervous system disorders Cerebrovascular disease 2.79 (2.21;3.54) 0 4.6 (3.7;5.6)
Epilepsy; convulsions Cerebrovascular disease 2.79 (2.09;3.73) + 5.3 (4.2;6.5)
  1. Abbreviations: CI confidence interval, LOS length of stay, OR odds ratio
  2. a20 combinations with the highest OR for PAR
  3. bA prolonged length of stay was defined as a stay longer than or equal to the upper quartile (75%)
  4. cThe signs "+" and "-"represent a significant more than multiplicative effect and less than multiplicative effect, respectively, of the comorbidities found in the combination on the odds for a prolonged LOS. A more than multiplicative effect means that the OR of the combination is higher than the ORs of the single comorbidities multiplied together. The sign "0"means that there is no significant interaction
  5. dp-value < 0.001 for all. A confidence interval not overlapping the zero line means that the difference in median is significant