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Table 6 Subgroup analyses: differences in treatment effects between subgroups (statistical test of interaction)

From: Feasibility and long-term efficacy of a proactive health program in the treatment of chronic back pain: a randomized controlled trial

Primary outcomes

Subgroups

Low risk (0–3) IG versus CG

Medium/High risk (> 3) IG versus CG

Back pain severity (CPGQ)

characteristic back pain intensity (0–100)

Mean Difference (SE) between IG / CG

- 1.0 (2.17)

+ 7.4 (2.69)

Δ of treatment effect in the both subgroups (SE)

8.4 (3.46)

z-score/ p

2.428/ 0.015

disability points (0–6)

mean difference (SE) between IG / CG

0.05 (0.22)

0.68 (0.28)

Δ of treatment effect in the both subgroups (SE)

0.63 (0.36)

z-score/ p

1.750 / 0.080

Health-related quality of life (SF-12)

physical component (0–100)

mean difference (SE) between IG / CG

0.9 (1.10)

3.9 (1.34)

Δ of treatment effect in the both subgroups (SE)

3.0 (1.73)

z-score/ p

1.734 / 0.083

mental component (0–100)

mean difference (SE) between IG / CG

- 2.1 (1.38)

2.7 (1.60)

Δ of treatment effect in the both subgroups (SE)

4.8 (2.11)

z-score/ p

2.275/ 0.023

  1. CPGQ Chronic Pain Grade Questionnaire according to v. Korff, SF-12 12 Items Short Form questionnaire, SE standard error, Δ: difference, p significance value