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Table 4 All-cause mortality by treatment period, by gender and age. Cox regression and 95% confidence intervals

From: From restrictive to more liberal: variations in mortality among patients in opioid maintenance treatment over a 12-year period

 

In-treatment (n = 6871)

After treatment (n = 1650)

HR (95% CI)

P-value

HR (95% CI)

P-value

Treatment period

 1997–1999 (reference)

  2000–2002

0.88 (0.67–1.18)

0.398

0.93 (0.34–2.57)

0.889

  2003–2005

0.71 (0.52–0.97)

0.33

0,56 (0.20–1.56)

0.266

  2006–2009

0.59 (0.39–0.98)

0.11

0.43 (0.51–1.20)

0.106

Gender

 Men (reference)

  Female

0.95 (0.76–2.20)

0.68

0.73 (0.54–1.00)

0.046

  Age Treatment start

1.07 (1.06–1.09)

< 0,001

0.99 (0.97–1.01)

0.577

  1. HR Hazard Ratio (estimated Hazard ratio for a one unit increase of change in the explanatory variable given the other variables held constant in the model)