Clinical Characteristics of Participants in Two Study Arms (At Baseline) [Mean ± SD]
|
---|
Parameters
|
Control Arm, n = 121
|
Intervention Arm, n = 123
|
p–values
|
Age (Yrs)
|
50.4 ± 7.7
|
50.3 ± 10.5
|
0.89
|
Age at diagnosis of DM(Yrs)
|
42.8 ± 7.9
|
44.2 ± 9.8
|
0.24
|
Duration of DM (Yrs)
|
7.6 ± 5.4
|
6.1 ± 5.3
|
0.029*
|
Haemoglobin (mg/dL)
|
13.2 4 ± 1.1
|
13.9 ± 1.1
|
0.69
|
Weight (Kg)
|
78.3 ± 14.4
|
77.5 ± 17.6
|
0.72
|
Waist (cm)
|
110 ± 16.5
|
109 ± 16.5
|
0.86
|
BMI (Kg/m
2
)
|
30.6 ± 4.9
|
30.8 ± 6.4
|
0.79
|
Systolic BP (mmHg)
|
133 ± 15.4
|
145 ± 20.9
|
0.0001**
|
Diastolic BP (mmHg)
|
85 ± 10.4
|
94 ± 10.7
|
0.0001**
|
eABG (mg/dL)
|
261 ± 49.8
|
268 ± 50.2
|
0.25
|
HbA1c
|
10.7 ± 1.7
|
11.0 ± 1.7
|
0.25
|
Cholesterol (mg/dL)
|
231 ± 55.7
|
223 ± 51.3
|
0.26
|
Triglycerides(mg/dL)
|
191 ± 79.7
|
272 ± 112.1
|
0.0001**
|
HDL-C (mg/dL)
|
48 ± 12.5
|
49 ± 18.2
|
0.45
|
LDL-C (mg/dL)
|
145 ± 48.5
|
119 ± 50.3
|
0.0001**
|
VLDL-C (mg/dL)
|
38 ± 15.9
|
54 ± 22.4
|
0.0001**
|
Serum Creatinine (mg/dL)
|
1.0 ± 0.3
|
1.1 ± 0.4
|
0.007*
|
Treatments
|
None
|
2 (1.7%)
|
1 (0.8%)
| |
OHA
|
66 (54.5%)
|
72 (58.5%)
|
0.51
|
OHA + Insulin
|
43 (35.5%)
|
45 (36.6%)
|
Insulin
|
10 (8.3%)
|
5 (4.1%)
|
- Abbreviation: SD Standard Deviation, DM Diabetes Mellitus, BMI Body Mass Index, eABG Estimated Average Blood Glucose, HbA1c Glycosylated Haemoglobin, HDL-C High Density Lipoprotein-Cholesterol, LDL-C Low Density Lipoprotein-Cholesterol, VLDL-C Very Low Density Lipoprotein-Cholesterol, OHA Oral Hypoglycaemic Agents, I Intervention, C Control, M Male, F Female
-
p-values; *p < 0.05–0.002, **p < 0.002–0.0001