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Table 4 Patient consumption profile and Human Health benefit and burden results

From: Human health benefit and burden of the schizophrenia health care pathway in Belgium: paliperidone palmitate long-acting injections

1. Patient consumption profile

TI

PP1M

PP3M

Syringes (1 M)

–

8055

94

Syringes (3 M)

–

–

2564

GP visits

2883

3322

3447

Psychiatrist visits

34,109

35,224

35,528

Ambulatory care visits

1849

701

371

General hospital bed days

791

335

178

Psychiatric hospital bed days

43,864

16,406

8699

2. Human Health benefit

Years Lived with Disability (YLD)

Total patient YLDs

626.80

603.49

596.90

ΔYLDs of treatment vs. TI (%)

–

−23.31 (−3.72%)

−29.91 (−4.77%)

Years of Life Lost (YLL)

Total patient YLLs

346.23

300.63

288.36

ΔYLL of treatment vs. TI (%)

–

−45.60 (−13.17%)

−57.87 (−16.71%)

Disability-Adjusted Life Years (DALY) = YLD + YLL

Total patient DALYs

973.03

904.12

885.26

ΔDALY of treatment vs. TI (%)

–

−68.91 (−7.08%)

−87.77 (−9.02%)

Quality-Adjusted Life Years (QALY)

Total patient QALYs

785.22

830.54

881.35

ΔQALY of treatment vs. TI (%)

–

+ 45.32 (+ 5.77%)

+ 96.13 (+ 12.24%)

3. Human Health burden

Environmental DALYs

Total environmental DALYs

0.954

0.579

0.468

ΔDALYs of treatment vs. TI (%)

–

−0.375 (−39.32%)

−0.487 (−51.00%)

4. Net Human Health effects (net DALYs = YLD + YLL + environmental DALYs)

Total net DALYs

973.98

904.70

885.73

ΔDALY of treatments vs. TI

–

−69.29 (−7.11%)

−88.26 (−9.06%)

  1. Abbreviations: PP1M, paliperidone palmitate once-monthly injection; PP3M, paliperidone palmitate three-monthly injection; TI, Treatment Interruption