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Table 1 Basic characteristics of the ICU cohort and patients treated with antibacterials

From: Is antibacterial treatment intensity lower in elderly patients? A retrospective cohort study in a German surgical intensive care unit

Characteristic All patients < 80 years ≥80 years p-value*
Full cohort
 Number of patients 17,464 14,824 (84.9%) 2640 (15.1%)  
 Patient days 76,424 67,480 8944  
 Length of stay (median, IQR (days)) 0.9 (0.8–2.6) 0.9 (0.8–2.7) 0.9 (0.8–2.0) 0.0004
 Female patients 7498 (42.9%) 5875 (39.6%) 1623 (61.5%) < 0.0001
 ICU mortality rate 1448 (8.3%) 1136 (7.7%) 312 (11.8%) < 0.0001
 SAPS II (median of means, IQR)a 20.1 (13.3–28.9) 19.9 (13.0–28.6) 22.0 (15.0–30.0) < 0.0001
 TISS-10 (median of means, IQR) 9.7 (5.0–12.5) 10.0 (5.7–12.6) 7.5 (5.0–11.1) < 0.0001
Patients treated with antibacterials
 Number of patients 5785 (33.1%b) 5060 (34.1%c) 725 (27.5%c) < 0.0001
 Patient days 44,936 40,831 4105  
 Length of stay (median, IQR (days)) 2.2 (0.9–8.7) 2.3 (0.9–9.1) 2.0 (0.9–5.7) 0.0142
 Female patients 2047 (35.4%) 1689 (33.4%) 358 (49.4%) < 0.0001
 ICU mortality rate 869 (15.0%) 726 (14.4%) 143 (19.7%) 0.0002
 SAPS II (median of means, IQR)a 24.6 (17.5–32.7) 24.4 (17.3–33.0) 25.8 (18.5–31.5) 0.4291
 TISS-10 (median of means, IQR) 10.7 (7.5–14.1) 10.8 (7.8–14.4) 9.0 (5.0–12.1) < 0.0001
 Exposed patient days 29,578 26,808 2770  
 Number of Antibacterial prescriptions 190,689 172,963 17,726  
 Therapy days 52,342 47,630 4712  
  1. *from Chi2-Test for proportions and Mann-Whitney-U-Test for continuous variables (two-sided with significance level of p < 0.05)
  2. aSAPS II calculated without age points
  3. bPercent of full cohort
  4. cPercent of age group