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Table 1 Basic characteristics of the ICU cohort and patients treated with antibacterials

From: Is antibacterial treatment intensity lower in elderly patients? A retrospective cohort study in a German surgical intensive care unit

Characteristic

All patients

< 80 years

≥80 years

p-value*

Full cohort

 Number of patients

17,464

14,824 (84.9%)

2640 (15.1%)

 

 Patient days

76,424

67,480

8944

 

 Length of stay (median, IQR (days))

0.9 (0.8–2.6)

0.9 (0.8–2.7)

0.9 (0.8–2.0)

0.0004

 Female patients

7498 (42.9%)

5875 (39.6%)

1623 (61.5%)

< 0.0001

 ICU mortality rate

1448 (8.3%)

1136 (7.7%)

312 (11.8%)

< 0.0001

 SAPS II (median of means, IQR)a

20.1 (13.3–28.9)

19.9 (13.0–28.6)

22.0 (15.0–30.0)

< 0.0001

 TISS-10 (median of means, IQR)

9.7 (5.0–12.5)

10.0 (5.7–12.6)

7.5 (5.0–11.1)

< 0.0001

Patients treated with antibacterials

 Number of patients

5785 (33.1%b)

5060 (34.1%c)

725 (27.5%c)

< 0.0001

 Patient days

44,936

40,831

4105

 

 Length of stay (median, IQR (days))

2.2 (0.9–8.7)

2.3 (0.9–9.1)

2.0 (0.9–5.7)

0.0142

 Female patients

2047 (35.4%)

1689 (33.4%)

358 (49.4%)

< 0.0001

 ICU mortality rate

869 (15.0%)

726 (14.4%)

143 (19.7%)

0.0002

 SAPS II (median of means, IQR)a

24.6 (17.5–32.7)

24.4 (17.3–33.0)

25.8 (18.5–31.5)

0.4291

 TISS-10 (median of means, IQR)

10.7 (7.5–14.1)

10.8 (7.8–14.4)

9.0 (5.0–12.1)

< 0.0001

 Exposed patient days

29,578

26,808

2770

 

 Number of Antibacterial prescriptions

190,689

172,963

17,726

 

 Therapy days

52,342

47,630

4712

 
  1. *from Chi2-Test for proportions and Mann-Whitney-U-Test for continuous variables (two-sided with significance level of p < 0.05)
  2. aSAPS II calculated without age points
  3. bPercent of full cohort
  4. cPercent of age group