Table 5 Parameters and variables examined in the probabilistic sensitivity analysis. Parameters with varied values
Parameter | Distribution | Mean | Range | |||
|---|---|---|---|---|---|---|
Outcomes | ||||||
 BMI reduction | Normal | 0.71 | 0.08 | – | 1.35 | (95% CI of mean) |
 Weight loss | Normal | 1.85 | 0.16 | – | 3.55 | (95% CI of mean) |
 CRP reduction, mg/L | Normal | 1.15 | 0.15 | – | 2.16 | (95% CI of mean) |
 Simple 7 increase | Normal | 0.67 | 0.14 | – | 1.21 | (95% CI of mean) |
 Annual ASCVD risk reduction | Log normal | 0.00096 | 0.00043 | – | 0.00149 | (95% CI of mean) |
Costs, per person | ||||||
 Resources of SHHC | Υ, gamma | 775 | 581 | – | 968 | (±25% of mean) |
 Resources of SHHC-CON | Υ, gamma | 667 | 500 | – | 833 | (±25% of mean) |
 Participant of SHHC | Υ, gamma | 1087 | 815 | – | 1359 | (±25% of mean) |
 Participant of SHHC-CON | Υ, gamma | 887 | 665 | – | 1108 | (±25% of mean) |
Medical cost, 2013 $ | ||||||
 CHD (nonfatal mi) | Υ, gamma | 62,200 | 52,870 | – | 71,530 | (±15% of mean) |
 Stroke (nonfatal) | Υ, gamma | 20,509 | 17,433 | – | 23,585 | (±15% of mean) |
 Follow-up visit, 2013 $ | Υ, gamma | 75 | 53 | – | 98 | (±30% of mean) |
QALYs | ||||||
 Women age 55–64, BMI 30–40 | β, beta | 0.798 | 0.678 | – | 0.918 | (±15% of mean) |
 CHD | β, beta | 0.697 | 0.592 | – | 0.802 | (±15% of mean) |
 Stroke | β, beta | 0.590 | 0.502 | – | 0.679 | (±15% of mean) |