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Table 4 Age, sex, health status and clinical details of HHCs diagnosed with active TB disease

From: Evaluation of facility and community-based active household tuberculosis contact investigation in Ethiopia: a cross-sectional study

HHC

Age

Sex

Symptoms at screening

TB Dx in index case

Mal-nutrition

Immuno-deficiencyd

Active TB diagnosis in HHCse

TB Site(s)

Diagnostic resultsf

Amhara Region

 1

58

M

Cough, night sweats, weight loss, appetite loss, fatigue

SS + PTB

No

No

EPTB

Cervical

AFB-negative SSM, normal CXR, suggestive FNAc

 2

53

M

Cough, night sweats, fatigue

EPTB

No

No

EPTB

Pleural

Abnormal CXR, suggestive body fluid analysis

 3

2

M

Fever, appetite loss

SS + PTB

Yes

No

PTB, no SSM

Pulmonary

Abnormal CXR

 4a

11

M

Fever, night sweats, weight loss, appetite loss

SS + PTB

No

No

PTB, no SSM

Pulmonary

Abnormal CXR

 5a

23

F

Cough, fever, night sweats, weight loss, appetite loss, fatigue

SS + PTB

No

No

SS + PTB

Pulmonary, cervical

AFB-positive SSM, abnormal CXR, suggestive FNAc

 6a

40

F

Cough, fever, night sweats, weight loss, appetite loss, fatigue

SS + PTB

No

No

EPTB

Pleural

AFB-negative SSM, abnormal CXR, suggestive FNAc, suggestive U/S

 7

14

F

Cough, neck swelling

EPTB

Yes

No

EPTB

Cervical

Suggestive FNAc

 8

55

M

Cough, fever

SS-PTB

Yes

Yes

SS-PTB

Pulmonary

AFB-negative SSM, abnormal CXR

 9

14

F

Cough, fever, night sweats, haemoptysis

EPTB

Yes

No

PTB, no SSM

Pulmonary

Abnormal CXR

 10

5

M

Cough, fever, appetite loss

EPTB

No

No

PTB, no SSM

Pulmonary

Abnormal CXR

 11

28

F

Fever, night sweats

EPTB

Yes

No

EPTB

Hilar lymph-adenopathy

Abnormal CXR

 12

30

F

Cough, fever, fatigue

EPTB

Yes

Yesc

EPTB

Axillary lymph-adenopathy

Normal CXR, suggestive FNAc

 13

8

M

Night sweats

EPTB

No

No

PTB, no SSM

Pulmonary, cervical

Abnormal CXR, suggestive FNAc

 14b

60

F

Cough, fever, night sweats, weight loss, appetite loss, fatigue

EPTB

Yes

No

EPTB

Pleural, cervical

AFB-negative SSM, abnormal CXR, suggestive FNAc

 15b

20

F

Cough, fever, night sweats

EPTB

Yes

Yes

PTB, no SSM

Pulmonary

Abnormal CXR

 16

10

M

Cough, fever, night sweats, appetite loss

EPTB

Yes

No

PTB, no SSM

Pulmonary

Abnormal CXR

 17

15

F

Cough, fever, night sweats, weight loss, neck swelling, fatigue

EPTB

Yes

No

PTB, no SSM

Pulmonary

Abnormal CXR, suggestive FNAc

 18

4

F

Fever, night sweats

EPTB

No

No

PTB, no SSM

Pulmonary

Abnormal CXR

Tigray Region

 19

14

F

Cough, weight loss

SS + PTB

Yes

No

SS + PTB

Pulmonary

AFB-positive SSM, abnormal CXR

  1. a, b Observed clustering (HHCs within the same household)
  2. cOnly HHC diagnosed with active TB disease with a positive HIV status
  3. dSelf-reported; includes HIV, kidney disease, diabetes, previous/current cancer treatment, previous TB, signs of primary immunodeficiency (e.g., recurrent or chronic infections)
  4. eSS-PTB Smear-negative pulmonary TB, SS + PTB smear-positive pulmonary TB, PTB pulmonary TB, no SSM sputum smear microscopy not performed, EPTB extra pulmonary TB
  5. fAFB acid-fast bacilli, SSM sputum smear microscopy, CXR chest x-ray, FNAc fine needle aspiration cytology, U/S ultrasound