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Table 1 Yield of household TB contact investigation by TB diagnosis of index

From: Evaluation of facility and community-based active household tuberculosis contact investigation in Ethiopia: a cross-sectional study

  All Forms TB EPTB Clinically Dx PTB SS+ PTB
Index cases 363 232 88 43
HHCs identified 1528 1031 357 140
HHCs screeneda (% of identified) 1509 (99) 1021 (99) 348 (97) 140 (10)
 Referreda (% of screened) 809 (54) 594 (58) 154 (44) 61 (44)
  <  5, no symptoms (% of referred) 78 (10) 60 (10) 17 (11) 1 (2)
  Symptoms (% of referred) 731 (90) 534 (90) 137 (89) 60 (98)
 Investigateda (% of referred) 763 (94) 557 (94) 151 (98) 55 (90)
 Testeda (% of investigated) 598 (78) 425 (76) 125 (83) 48 (87)
  SSMb(% of tested) 175 (29) 100 (24) 52 (42) 23 (48)
  GeneXpertb(% of tested) 7 (1) 7 (1) 0 (0) 0 (0)
  Otherc(% of tested) 416 (70) 318 (75) 73 (58) 25 (52)
 Diagnoseda (% Yieldd) 19 (1.3) 12 (1.2) 1 (0.3) 6 (4.3)
Yield per 100,000 (95% CIe) 1259 (759–1959) 1175 (609–2044) 287 (7–1591) 4286 (1589–9095)
NNS (95% CI) 79 (55–132) 85 (49–164) 348 (63–1375) 23 (11–63)
  1. Abbreviations: TB tuberculosis, EPTB Extra pulmonary TB, PTB Pulmonary TB, DX Diagnosed, SS+ sputum smear positive, SSM sputum smear microscopy, NNS number needed to screen to detect one TB case
  2. aPresented as n (%) unless otherwise indicated
  3. bIndicated test ± any test indicated in the subsequent rows
  4. cOther tests included histopathology (FNAc), imaging (CXR, ultrasound), or other body fluid analysis
  5. dPercent (%) yield calculated as number diagnosed with TB divided by the number screened
  6. eYield per 100,000 with 95% confidence interval using exact binomial method
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