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Table 1 Yield of household TB contact investigation by TB diagnosis of index

From: Evaluation of facility and community-based active household tuberculosis contact investigation in Ethiopia: a cross-sectional study

 

All Forms TB

EPTB

Clinically Dx PTB

SS+ PTB

Index cases

363

232

88

43

HHCs identified

1528

1031

357

140

HHCs screeneda (% of identified)

1509 (99)

1021 (99)

348 (97)

140 (10)

 Referreda (% of screened)

809 (54)

594 (58)

154 (44)

61 (44)

  <  5, no symptoms (% of referred)

78 (10)

60 (10)

17 (11)

1 (2)

  Symptoms (% of referred)

731 (90)

534 (90)

137 (89)

60 (98)

 Investigateda (% of referred)

763 (94)

557 (94)

151 (98)

55 (90)

 Testeda (% of investigated)

598 (78)

425 (76)

125 (83)

48 (87)

  SSMb(% of tested)

175 (29)

100 (24)

52 (42)

23 (48)

  GeneXpertb(% of tested)

7 (1)

7 (1)

0 (0)

0 (0)

  Otherc(% of tested)

416 (70)

318 (75)

73 (58)

25 (52)

 Diagnoseda (% Yieldd)

19 (1.3)

12 (1.2)

1 (0.3)

6 (4.3)

Yield per 100,000 (95% CIe)

1259 (759–1959)

1175 (609–2044)

287 (7–1591)

4286 (1589–9095)

NNS (95% CI)

79 (55–132)

85 (49–164)

348 (63–1375)

23 (11–63)

  1. Abbreviations: TB tuberculosis, EPTB Extra pulmonary TB, PTB Pulmonary TB, DX Diagnosed, SS+ sputum smear positive, SSM sputum smear microscopy, NNS number needed to screen to detect one TB case
  2. aPresented as n (%) unless otherwise indicated
  3. bIndicated test ± any test indicated in the subsequent rows
  4. cOther tests included histopathology (FNAc), imaging (CXR, ultrasound), or other body fluid analysis
  5. dPercent (%) yield calculated as number diagnosed with TB divided by the number screened
  6. eYield per 100,000 with 95% confidence interval using exact binomial method