Reviews meeting the criteria (n) | Tool question | Reviews meeting the criteria (n) | |||
---|---|---|---|---|---|
Yes | No | Unable to determine | Not applicable | ||
1.Background | 1.1. Are the terms sex and gender used in the background? | 12 | 90 | 0 | 11 |
1.2. Are sex/gender identified as relevant or not to review question? | 2 | 92 | 8 | 11 | |
1.3. Does background discuss why sex/gender differences may be expected? | 0 | 102 | 0 | 11 | |
2. Objectives | 2.1. Are the terms sex, gender, male, or female used in objectives? | 0 | 102 | 0 | 11 |
3.Criteria for inclusion-exclusion | 3.1. Do the review’s inclusion-exclusion criteria consider sex-gender differences? | 0 | 102 | 0 | 11 |
3.2. Was there justification or explanation for the exclusion of some groups? | 0 | 102 | 0 | 11 | |
4. Methods | 4.1. Does the review examine whether outcome measures are different for males and females? | 0 | 102 | 0 | 11 |
4.2. Did the review extract data by sex? | 0 | 102 | 0 | 11 | |
4.3. Did the review extract data on sex of withdrawals and dropouts? | 0 | 102 | 0 | 11 | |
4.4. In cases where sex/gender is used as a proxy, is there an explanation? | 0 | 0 | 0 | 113 | |
4.5. Were any subgroup analyses completed? | 41 | 61 | 0 | 11 | |
4.6. Were subgroup analyses by sex completed? | 3 | 99 | 0 | 11 | |
5.Results and analysis | 5.1. Do results distinguish between findings for males/females? | 0 | 96 | 1 | 16 |
5.2. Does the review report conclusions that are different for men and women? | 0 | 96 | 1 | 16 | |
5.3. If adverse effects are reported, is information sex-disaggregated? | 0 | 60 | 0 | 53 | |
5.4. Does review note that subgroup analyses by sex could not be done? | 7 | 3 | 1 | 102 | |
6. Discussion and conclusion | 6.1. Does the review report that primary studies analysed or failed to analyse results by sex? | 0 | 97 | 0 | 16 |
6.2. Does the review address sex/gender implications for clinical practice? | 1 | 101 | 0 | 11 | |
6.3. Does the review address sex/gender implications for policy and regulation? | 0 | 102 | 0 | 11 | |
6.4. Does the review address sex/gender implications for research? | 2 | 100 | 0 | 11 | |
7. Table of included studies | 7.1. Detailed information on sex/gender of the study samples? | 0 | 97 | 0 | 16 |