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Table 4 Responses to the Sex and Gender Appraisal Tool for Systematic Reviews (SGAT-SR)

From: Consideration of sex and gender in Cochrane reviews of interventions for preventing healthcare-associated infections: a methodology study

Reviews meeting the criteria (n) Tool question Reviews meeting the criteria (n)
Yes No Unable to determine Not applicable
1.Background 1.1. Are the terms sex and gender used in the background? 12 90 0 11
1.2. Are sex/gender identified as relevant or not to review question? 2 92 8 11
1.3. Does background discuss why sex/gender differences may be expected? 0 102 0 11
2. Objectives 2.1. Are the terms sex, gender, male, or female used in objectives? 0 102 0 11
3.Criteria for inclusion-exclusion 3.1. Do the review’s inclusion-exclusion criteria consider sex-gender differences? 0 102 0 11
3.2. Was there justification or explanation for the exclusion of some groups? 0 102 0 11
4. Methods 4.1. Does the review examine whether outcome measures are different for males and females? 0 102 0 11
4.2. Did the review extract data by sex? 0 102 0 11
4.3. Did the review extract data on sex of withdrawals and dropouts? 0 102 0 11
4.4. In cases where sex/gender is used as a proxy, is there an explanation? 0 0 0 113
4.5. Were any subgroup analyses completed? 41 61 0 11
4.6. Were subgroup analyses by sex completed? 3 99 0 11
5.Results and analysis 5.1. Do results distinguish between findings for males/females? 0 96 1 16
5.2. Does the review report conclusions that are different for men and women? 0 96 1 16
5.3. If adverse effects are reported, is information sex-disaggregated? 0 60 0 53
5.4. Does review note that subgroup analyses by sex could not be done? 7 3 1 102
6. Discussion and conclusion 6.1. Does the review report that primary studies analysed or failed to analyse results by sex? 0 97 0 16
6.2. Does the review address sex/gender implications for clinical practice? 1 101 0 11
6.3. Does the review address sex/gender implications for policy and regulation? 0 102 0 11
6.4. Does the review address sex/gender implications for research? 2 100 0 11
7. Table of included studies 7.1. Detailed information on sex/gender of the study samples? 0 97 0 16