Table 1 Evidence for the effectiveness of anti-hypertensive drugs in NRDL of UEBMI——From the international evidence-based drug list
| Â | Dosage form | JNC 8 | NICE 2011 | WHO EML 2017 | Frequency of inclusion |
|---|---|---|---|---|---|
Calcium antagonist | |||||
 Class A | |||||
  Amlodipine | oral release dosage form | √ | √ | √ | 3 |
  Nimodipine | oral release dosage form | – | – | – | 0 |
  Nitrendipine | oral release dosage form | – | – | – | 0 |
  Nifedipine | oral release dosage form | – | √ | √ | 2 |
  Diltiazem | oral release dosage form | – | √ | √ | 2 |
  Verapamil | oral release dosage form | – | √ | √ | 2 |
  Verapamil | injection | – | – | √ | 1 |
 Class B | |||||
  L - nmda amlodipine | oral release dosage form | – | – | – | 0 |
  Amlodipine atorvastatin calcium | oral release dosage form | – | – | – | 0 |
  Benidipine | oral release dosage form | – | – | – | 0 |
  Felodipine | oral release dosage form, controlled release dosage form | – | √ | – | 1 |
  Felodipine II | controlled release dosage form | – | √ | – | 1 |
  Lacidipine | oral release dosage form | – | √ | – | 1 |
  Lercanidipine | oral release dosage form | – | √ | – | 1 |
  Nicardipine | oral release dosage form, controlled release dosage form | – | – | – | 0 |
  Nicardipine | injection | – | – | – | 0 |
  Nimodipine | injection | – | – | – | 0 |
  Nitrendipine and Atenolol | oral release dosage form | – | – | – | 0 |
  Cilnidipine | oral release dosage form | – | – | – | 0 |
  Nifedipine (I,II,III) | controlled release dosage form | – | √ | √ | 2 |
  Levamlodipine besylate tablets | oral release dosage form | – | √ | – | 1 |
  Diltiazem | injection | – | – | – | 0 |
  Diltiazem (II) | controlled release dosage form | – | √ | √ | 2 |
  Verapamil | controlled release dosage form | – | √ | √ | 2 |
β blockers | |||||
 Class A | |||||
  Propranolol | oral release dosage form | – | √ | √ | 2 |
  Atenolol | oral release dosage form | √ | √ | – | 2 |
  Bisoprolol | oral release dosage form | – | √ | √ | 2 |
  Metoprolol | oral release dosage form | √ | √ | – | 2 |
  Metoprolol | injection | – | – | – | 0 |
 Class B | |||||
  Propranolol | Sustained or controlled release dosage form | – | √ | √ | 2 |
  Propranolol | injection | – | – | – | 0 |
  Sotalol | oral release dosage form | – | √ | – | 1 |
  Sotalol | injection | – | – | – | 0 |
  Esmolol | injection | – | – | – | 0 |
  Metoprolol | controlled release dosage form | √ | √ | – | 2 |
  Arotinolol | oral release dosage form | – | – | – | 0 |
  Carvedilol | oral release dosage form | – | – | – | 0 |
  Labetalol | oral release dosage form | – | – | – | 0 |
diuretics | |||||
 Class A | |||||
  Hydrochlorthiazide | oral release dosage form | √ | √ | √ | 3 |
  Indapamide | oral release dosage form, controlled release dosage form | √ | √ | – | 2 |
  Furosemide | oral release dosage form | – | – | √ | 1 |
  Furosemide | injection | – | – | √ | 1 |
  Triamterene | oral release dosage form | – | – | – | 0 |
  Spironolactone | oral release dosage form | – | √ | √ | 2 |
 Class B | |||||
  Bumetanide | oral release dosage form | – | – | – | 0 |
  Bumetanide | injection | – | – | – | 0 |
  Torasemide | oral release dosage form | – | – | – | 0 |
  Torasemide | injection | – | – | – | 0 |
  Amiloride | oral release dosage form | – | √ | √ | 2 |
ACEIs | |||||
 Class A | |||||
  Captopril | oral release dosage form | √ | √ | – | 2 |
  Enalapril | oral release dosage form | √ | √ | √ | 3 |
 Class B | |||||
  Benazepril | oral release dosage form | – | – | – | 0 |
  Fosinopril | oral release dosage form | – | – | – | 0 |
  Lisinopril | oral release dosage form | √ | √ | – | 2 |
  Ramipril | oral release dosage form | – | √ | – | 1 |
  Imidapril | oral release dosage form | – | – | – | 0 |
  Perindopril | oral release dosage form | – | √ | – | 1 |
  Cilazapril | oral release dosage form | – | – | – | 0 |
  Amlodipine benapril I (II) | oral release dosage form | – | – | – | 0 |
  Benapril hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
  compound captopril | oral release dosage form | – | – | – | 0 |
  Lynopli hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
  Enalpril hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
  Enopril folic acid | oral release dosage form | – | – | – | 0 |
Angiotensin II receptor antagonist | |||||
 Class B | |||||
  Olmesartan Medoxomil | oral release dosage form | – | – | – | 0 |
  Irbesartan | oral release dosage form, controlled release dosage form | √ | √ | – | 2 |
  Candesartan | oral release dosage form | √ | √ | – | 2 |
  Losartan | oral release dosage form | √ | √ | √ | 3 |
  Telmisartan | oral release dosage form | √ | √ | – | 2 |
  Valsartan | oral release dosage form | √ | √ | – | 2 |
  Omethane hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
  irbesartan hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
  chlorothiazide | oral release dosage form | – | – | – | 0 |
  Timisaltan hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
  Valsartan chlordipine I (II) | oral release dosage form | – | – | – | 0 |
  Valsartan hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
vasodilators | |||||
 Class A | |||||
  Phentolamine | injection | – | – | – | 0 |
  Sodium nitroprusside | injection | – | – | √ | 1 |
 Class B | |||||
  Phenoxybenzamine | oral release dosage form | – | – | – | 0 |
  Phenoxybenzamine | injection | – | – | – | 0 |
  Hydralazine | oral release dosage form | – | – | √ | 1 |
  Hydralazine | injection | – | – | √ | 1 |
  Minoxidil | oral release dosage form | – | – | – | 0 |
Others | |||||
 Class A | |||||
  Reserpine | injection | – | – | – | 0 |
  Prazosin | oral release dosage form | – | √ | – | 1 |
  Compound reserpine | oral release dosage form | – | – | – | 0 |
  Compound reserpine ammonia benzene pteridine | oral release dosage form | – | – | – | 0 |
 Class B | |||||
  Dibazole | oral release dosage form | – | – | – | 0 |
  Methyldopa | oral release dosage form | – | √ | √ | 2 |
  Clonidine | oral release dosage form | – | – | – | 0 |
  Clonidine | Patch | – | – | – | 0 |
  Reserpine | oral release dosage form | – | – | – | 0 |
  Ligustrazine | Injection | – | – | – | 0 |
  Doxazosin | oral release dosage form, controlled release dosage form | – | √ | – | 1 |
  Naftopidil | oral release dosage form | – | – | – | 0 |
  Urapidil | oral release dosage form, controlled release dosage form | – | – | – | 0 |
  Urapidil | injection | – | – | – | 0 |