Table 2 Antibiotic agents prescribed among the study hospitals (% of prescribed antibiotics)
Medical | surgical | |||||
|---|---|---|---|---|---|---|
Antibiotic prescriptions (ATC4) | Antrim Area Hospital (n = 239 antibiotic prescriptions) n (%) | Specialty Hospital (n = 65 antibiotic prescriptions) n (%) | p value | Antrim Area Hospital (n = 66 antibiotic prescriptions) n (%) | Specialty Hospital (n = 56 antibiotic prescriptions) n (%) | p value |
Intestinal anti-infectives (antibiotics) (A07AA) | 6 (2.5) | 0 (0.0) | 0.197 | 0 (0.0) | 0 (0.0) | n/a |
Tetracyclines (J01AA) | 21 (8.8) | 3 (4.6) | 0.269 | 1 (1.5) | 2 (3.6) | 0.465 |
Penicillins with extended spectrum (J01CA) | 45 (18.8) | 0 (0.0) | < 0.001 | 9 (13.6) | 0 (0.0) | 0.004 |
Beta-lactamase sensitive penicillins (J01 CE) | 4 (1.7) | 0 (0.0) | 0.294 | 0 (0.0) | 0 (0.0) | n/a |
Beta-lactamase resistant penicillins (J01CF) | 10 (4.2) | 0 (0.0) | 0.094 | 2 (3.0) | 0 (0.0) | 0.189 |
Combinations of penicillins, including b-lactamase inhibitors (J01CR) | 45 (18.8) | 8 (12.3) | 0.219 | 13 (19.7) | 4 (7.1) | 0.046 |
First-generation cephalosporins (J01DB) | 1 (0.4) | 1 (1.5) | 0.322 | 1 (1.5) | 2 (3.6) | 0.465 |
Second-generation cephalosporins (J01 DC) | 4 (1.7) | 0 (0.0) | 0.294 | 0 (0.0) | 2 (3.6) | 0.122 |
Third-generation cephalosporins (J01DD) | 5 (2.1) | 17 (26.2) | < 0.001 | 0 (0.0) | 21 (37.5) | < 0.001 |
Monobactams (J01DF), | 7 (2.9) | 0 (0.0) | 0.163 | 0 (0.0) | 0 (0.0) | n/a |
Carbapenems (J01DH) | 3 (1.3) | 10 (15.4) | < 0.001 | 1 (1.5) | 12 (21.4) | < 0.001 |
Trimethoprim and derivatives (J01EA) | 4 (1.7) | 0 (0.0) | 0.294 | 1 (1.5) | 0 (0.0) | 0.355 |
Combination of trimethoprim/sulfamethoxazole (J01EE) | 6 (2.5) | 0 (0.0) | 0.197 | 0 (0.0) | 0 (0.0) | n/a |
Macrolides (J01FA) | 23 (9.6) | 3 (4.6) | 0.201 | 0 (0.0) | 0 (0.0) | n/a |
Aminoglycosides (J01GB) | 11 (4.6) | 6 (9.2) | 0.150 | 13 (19.7) | 1 (1.8) | 0.002 |
Fluoroquinolones (J01MA) | 3 (1.3) | 12 (18.5) | < 0.001 | 2 (3.0) | 3 (5.4) | 0.518 |
Glycopeptide antibacterials (J01XA) | 12 (5.0) | 2 (3.1) | 0.507 | 4 (6.1) | 7 (12.5) | 0.216 |
Steroid antibacterials (J01XC) | 1 (0.4) | 0 (0.0) | 0.601 | 0 (0.0) | 0 (0.0) | n/a |
Imidazole derivatives (J01XD) | 18 (7.5) | 2 (3.1) | 0.199 | 16 (24.2) | 2 (3.6) | 0.001 |
Nitrofuran derivatives (J01XE) | 2 (0.8) | 0 (0.0) | 0.459 | 0 (0.0) | 0 (0.0) | n/a |
Other antibacterials (J01XX) | 0 (0.0) | 1 (1.5) | 0.055 | 1 (1.5) | 0 (0.0) | 0.355 |
Antimycotics, triazole derivatives (J02 AC) | 2 (0.8) | 0 (0.0) | 0.459 | 0 (0.0) | 0 (0.0) | n/a |
Antimycotics, other antimycotics for systematic use (J02AX) | 1 (0.4) | 0 (0.0) | 0.601 | 0 (0.0) | 0 (0.0) | n/a |
Antimycobacterials, antibiotics (J04AB) | 5 (2.1) | 0 (0.0) | n/a | 0 (0.0) | 0 (0.0) | n/a |
Antivirals, neuraminidase inhibitors (J05AH) | 0 (0.0) | 0 (0.0) | n/a | 0 (0.0) | 0 (0.0) | n/a |
Antiprotozoals, nitroimidazole derivatives (P01AB) | 5 (2.1) | 1 (0.8) | 0.240 | 2 (3.0) | 0 (0.0) | 0.189 |