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Table 4 Multivariable analysis of factors associated with NGS ≥ 5%

From: Factors influencing the use of the “not for generic substitution” mention for prescriptions in primary care: a survey with general practitioners

Variable Adjusted Odds Ratio (aOR) 95% Confidence Interval (95% CI) p value
INNa: <  15% 1.08 0.62–1.90 0.78
Practice: in cities (versus rural areas) 1.59 0.93–2.74 0.09
EPSb 0.46 0.20–1.05 0.07
Higher efficacy of brand-name drug 1.52 0.70–3.30 0.29
Does not believe in bioequivalence 0.92 0.41–2.05 0.84
Patient request 2.52 1.46–4.35 0.001
Patient comorbidity 2.79 0.96–8.04 0.06
Polypharmacy 1.00 0.37–2.73 0.99
Age of patient over 65 years 2.33 1.03–5.30 0.04
  1. aINN International Nonproprietary Name
  2. bEPS e-Prescription System