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Table 3 Causes of albumin and pantoprazole disapproval within the intervention period

From: Clinical and economical impacts of guideline implementation by the pharmaceutical care unit for high cost medications in a referral teaching hospital

Albumin

Pantoprazole

Cause of disapproval

Number (%)

Cause of disapproval

Number (%)

Management of edema in patients with serum albumin level above 2 g/dL

73 (24.58)

Ability to tolerate an oral PPI

246 (53.02)

A component of parenteral nutrition

59 (19.87)

Presence of only one minor risk factor for stress-related mucosal damage prophylaxis

115 (24.78)

Monotherapy of edema without a loop diuretic

36 (12.12)

Treatment of acute pancreatitis

29 (6.25)

Therapeutic paracentesis with ascitic fluid removal less than 5 L

21 (7.07)

Treatment of acute cholangitis or cholecystitis

21 (4.53)

Monotherapy of hepatorenal syndrome without a vasoactive agent

17 (5.72)

Gastric and/or pancreas cancer

17 (3.66)

Prolonged prevention (more than 2 weeks) of cerebral vasospasm in patients with subarachnoid hemorrhage

11 (3.7)

Lower GI obstruction or bleeding

15 (3.23)

Non-ARDS condition

3 (1.01)

Non-refractory (mild) dyspepsia

9 (1.94)

Others (no specific explanation)

42 (14.14)

Others (no specific explanation)

12 (2.59)

  1. ARDS Acute respiratory distress syndrome, PPI Proton pump inhibitor, GI Gastrointestinal