Un-adjusted PR | [95% CI], p | Adjusted PR | [95% CI], p | |
---|---|---|---|---|
General characteristics | ||||
Male | Ref. | Ref. | ||
Female | 1.39 | [1.36, 1.41], 0.000 | 1.52 | [1.51, 1.53], 0.000 |
Age at the beginning of diabetes (years) | 1.01 | [0.99, 1.03], 0.302 | 1.01 | [1.01, 1.02], 0.000 |
Schooling | ||||
Secondary school or less | Ref. | Ref. | ||
High school or technical or commercial career | 0.95 | [0.65, 1.39], 0.781 | 1.69 | [1.41, 2.02], 0.000 |
University degree or higher | 0.81 | [0.65, 1.00], 0.050 | 2.18 | [1.38, 3.44], 0.001 |
Active smoking | ||||
No | Ref | Ref. | ||
Yes | 1.20 | [0.70, 2.06], 0.504 | 1.28 | [0.72, 2.30], 0.402 |
Regular light to moderate alcohol consumption | ||||
No | Ref | Ref | ||
Yes | 0.56 | [0.44, 0.72], 0.000 | 0.68 | [0.61, 0.75], 0.000 |
Clinical characteristics | ||||
Diabetes duration, years | 0.99 | [0.96, 1.04], 0.869 | 0.98 | [0.96, 1.01], 0.118 |
HbA1C (%) | 0.98 | [0.89, 1.08], 0.717 | 0.95 | [0.86, 1.04], 0.258 |
Severe acute diabetic complications | ||||
No | Ref. | Ref. | ||
Yes | 4.05 | [2.00, 8.20], 0.000 | 7.54 | [4.07, 13.98], 0.000 |
Severe acute diabetic complications## HbA1C | 0.99 | [0.87, 1.13], 0.927 | 0.93 | [0.90, 0.95], 0.000 |
Microvascular chronic complications | ||||
No | Ref. | Ref. | ||
Yes | 1.89 | [1.19, 3.01], 0.007 | 2.01 | [1.99, 2.02], 0.000 |
Macrovascular chronic complications | ||||
No | Ref. | Ref. | ||
Yes | 1.60 | [0.81, 3.16], 0.174 | 1.18 | [1.13, 1.24], 0.000 |
Depression | ||||
No | Ref. | Ref. | ||
Yes | 2.21 | [0.84, 5.83], 0.107 | 1.72 | [1.00, 2.94], 0.049 |
Other comorbidities | ||||
No | Ref. | Ref. | ||
Yes | 1.43 | [1.33, 1.54], 0.000 | 1.27 | [1.26, 1.29], 0.000 |
Body mass index (kg/m2) | 0.94 | [0.92, 0.96], 0.000 | 0.95 | [0.92, 0.99], 0.013 |
Insulin therapy | ||||
Insulin monotherapy | Ref. | Ref. | ||
Combination of intermediate and fast acting insulin | 0.76 | [0.74, 0.77], 0.000 | 0.89 | [0.81, 0.97], 0.008 |
Combination of fast-acting and long-acting insulin | 0.85 | [0.50, 1.43], 0.536 | 1.05 | [0.63, 1.75], 0.857 |
Number of consultations with endocrinologist | 1.13 | [1.06, 1.20], 0.000 | 1.09 | [1.06, 1.11], 0.000 |