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Table 2 Summary of systematic review characteristics

From: Integration of care for hypertension and diabetes: a scoping review assessing the evidence from systematic reviews and evaluating reporting

Review

Search date

Number of studies included

Population and country where study was conducted

Intervention

Comparator

Outcomes

Atlantis 2014 [23]

August 2013

7

Adults diagnosed with depression and co-morbid diabetes

Australia: 1 study

USA: 6 studies

RCT: 7

Range of number of participants in each study: 58–417

Integrated care: 2 studies

Collaborative care: 5 studies

Type of integration:

Vertical

Clinical

Usual care: 4 studies Enhanced usual care: 3 studies

Depression score outcome

• CES-D 20 in 1 study

• PHQ-9 in 2 studies

• SCL-20 in 4 studies

Glycaemic control by HbA1c

Huang 2013 [24]

27 March 2013

8

Patients with depression and diabetes

One trial included only African Americans and two trials included only old patients (aged over 50 and 60 year old respectively)

USA: all studies

RCT: 8

Range of number of participants in each study: 58–417

Integrated management: 2 studies

Program to Encourage Active, Rewarding Lives for Seniors (PEARLS): 1 study

Multifaceted Diabetes and Depression Program (MDDP): 1 study

Collaborative care: 1 study

Stepped collaborative care: 1 study

An individualized stepped-care depression treatment program: 1 study

Improving Mood Promoting Access to Collaborative Treatment (IMPACT): 1 study

Type of integration:

Vertical

Professional

Clinical

Normal usual care: 5 trials

Enhanced usual care: 3 trials

Depression treatment response and depression remission at the end of follow-up

Depression treatment response at 6 and 12 months follow-up

Depression remission at 6 and 12 months follow-up

Diabetes clinical outcomes (HbA1c values) at the end of follow-up

Diabetes clinical outcomes (HbA1c values) at 6 and 12 months follow-up

Adherence to medication (including adherence of oral hypoglycemic agents and/or antidepressants)

Joshi 2014 [25]

26 May – 13 June, 2013

22 total in review; 4 of relevance

Task-shifting for the management of hypertension and cardiovascular diseases: 7 studies

Task-shifting for the management of diabetes: 5 studies

Cameroon: 3 studies

South Africa: 1 study

Before-after study: 3

RCT:1

Range of number of participants in each study: 221–1343

Task-shifting for the management of non-communicable disease

Task shifting from:

Physicians to health workers: 4 studies

Type of integration:

Vertical

Professional

Clinical

Usual healthcare: 4 studies

Process outcomes

Disease outcomes

Treatment concordance

Cost-effectiveness

Enablers for task-shifting

Barriers to task-shifting

Smith 2016 [26]

28 Sept, 2015

18 total in review; 6 of relevance

Hypertension and depression: 1 study

Depression and diabetes/heart disease: 3 studies

Hypertension and diabetes: 2 studies

Australia: 1 study

UK: 1 study

USA: 4 studies

Cluster RCT: 1

RCT: 4

RCT (pilot): 1

Range of number of participants in each study: 61–400

Change to organisation of care delivery through case management or enhanced multidisciplinary team work: 5 studies

Patient-oriented, such as educational or self-management support-type interventions: 3 study

Type of integration:

Vertical

Professional

Clinical

Usual care: 2 studies

Usual care additional services: 3 studies

Enhanced primary care: 1 studies

Patient clinical or mental health outcomes

Patient-reported outcome measures

Utilisation of health services

Patient behaviour

Provider behaviour

Acceptability of the service to recipients and providers, and treatment satisfaction

Economic outcomes

Watson 2013 [27]

11 June, 2012

12 studies; 3 studies of relevance

Adults (mean age = 59 years) and various chronic medical conditions, including 3 studies of relevance focusing on diabetes and depression

USA: all studies

RCT: 2 studies

Preplanned sub-group analysis from a separate randomized controlled trial: 1 study

Range of number of participants in each study: 329–417

All included studies characterized their respective intervention as a form of collaborative care, not another form of a practice-based intervention (such as integrated care)

Type of integration:

Vertical

Professional

Clinical

Enhanced usual care: 2 studies (9 articles)

Usual care: 1 study (2 articles)

Mental health outcomes

Chronic medical outcomes

Harms

  1. RCT randomized controlled trial, USA United States of America