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Table 1 Markov model inputs

From: Cost-effectiveness analysis of guideline-based optimal care for venous leg ulcers in Australia

Variables Value References
Transition probabilitiesa
Usual care
 Probability of healing (3-month) 0.2281 [19]
 Probability of recurrence (annual) 0.5574 [20]
 Probability of hospitalisation (5-year) 0.24 [22]
Optimal care
 Probability of healing (3-month) 0.5872 [19]
 Probability of recurrence (annual) 0.2222 [5]
 Probability of hospitalisation (annual) 0.0116 [21]
VLU Incidence rate (annual) 0.0121 [18]
All-cause mortality rate (annual) 0.0282 Calculated from ABS data [15]
Proportion of unhealed ulcers with infection   
Usual care 10% [24]
Optimal care 5% [24]
Cost itemsb
 GP AUD 71.70 MBS item 36
 Nurse practitioner AUD 58.55 MBS item 82215
 Vascular surgeon AUD 85.55 MBS item 104
 Community nurse hourly wage rate AUD 24.74–37.05 [31,32,33,34,35,36,37,38]
 Ankle-brachial pressure index (ABPI) assessment AUD 63.74 MBS item 11610
 Pathology test AUD 33.75 MBS item 69306
 Compression bandage AUD 51.5 Retail price
 Compression stocking AUD 97.75 Retail price
 Complicated VLU with hospitalisation AUD 18,331.60 [23]
Quality of life utility score
 Healed VLU 0.75 [25]
 Unhealed VLU 0.64 [25]
 Complicated VLU with hospitalisation 0.54 calculated
  1. aYearly or monthly probabilities were transformed to fortnightly probabilities by the formula: tp = 1 – (1 - tpt)1/t [14]
  2. bCosts for health states by State and Territories in Australia are presented in Additional file 1 Table S4