Parameter uncertainty

Uncertainty in estimates of the values of the parameters used in the costeffectiveness model, represented by the familiar concepts of standard deviation and standard error

Probabilistic sensitivity analysis

Structural uncertainty

The assumptions made in constructing and populating costeffectiveness models, such as the method used to extrapolate survival

Sensitivity analysis

Methodological uncertainty

The analytical approaches used

Specification of a Reference Case of standard methods

Generalisability

To what extent the model, assumptions and data represent the population for which the decision is being made

Sensitivity analysis
